CAS 118421-50-4

Glutathione monoethyl ester

Description:

Glutathione monoethyl ester is a derivative of glutathione, a tripeptide composed of glutamate, cysteine, and glycine, which plays a crucial role in cellular antioxidant defense and detoxification processes. The monoethyl ester form enhances the bioavailability of glutathione, allowing for improved cellular uptake. This compound is typically characterized by its ability to act as a reducing agent, helping to maintain the redox balance within cells. It is often utilized in research settings to study the effects of glutathione on various biological processes, including oxidative stress and cellular signaling pathways. Additionally, glutathione monoethyl ester may exhibit protective effects against cellular damage induced by reactive oxygen species (ROS). Its solubility in water and compatibility with various biological systems make it a valuable tool in pharmacological and biochemical studies. However, as with any chemical substance, proper handling and safety precautions should be observed, given its potential reactivity and effects on biological systems.

Formula: C₁₂H₂₁N₃O₆S

InChI: InChI=1/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1

SMILES: CCOC(=O)CN=C([C@H](CS)N=C(CC[C@@H](C(=O)O)N)O)O

Synonyms:

• Glutathione monoethyl ester
• Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl-, monoethyl ester
• Glycine, N-(N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl)-, monoethyl ester
• Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-, monoethyl ester
• Ione Ethyl Ester
• N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine monoethyl ester
• ethyl L-gamma-glutamyl-L-cysteinylglycinate
• Glycine, N-(N-L-γ-glutamyl-L-cysteinyl)-, monoethyl ester
• Glycine, L-γ-glutamyl-L-cysteinyl-, monoethyl ester

N-(N-L-γ-Glutamyl-L-cysteinyl)glycine monoethyl ester

CAS: 118421-50-4

Formula: C₁₂H₂₁N₃O₆S

Molecular weight: 335.3766

Ref: IN-DA007QB1

Glutathione reduced ethyl ester

CAS: 118421-50-4

Glutathione reduced ethyl ester

Color and Shape: Solid

Molecular weight: 335.38g/mol

Ref: 54-BIB6290

Glutathione reduced ethyl ester

CAS: 118421-50-4

Glutathione reduced ethyl ester (GR-E) is a potential anticancer drug that binds to the DNA and induces reactive oxygen species. GR-E has been shown to have minimal toxicity in vivo, with no observable adverse effects on the liver. GR-E has also been shown to be effective in treating squamous cell carcinoma cells by binding to their DNA and inducing apoptosis. This drug had minimal toxicity in animal studies, with no observable adverse effects on the liver. GR-E has been shown to be effective in treating squamous cell carcinoma cells by binding to their DNA and inducing apoptosis. This drug had minimal toxicity in animal studies, with no observable adverse effects on the liver. GR-E has also been shown to bind to toll-like receptor 2, which may lead to an antiinflammatory response.

Formula: C₁₂H₂₁N₃O₆S

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 443.47 g/mol

Ref: 3D-FG03344

Glutathione Monoethyl Ester

CAS: 118421-50-4

Formula: C₁₀H₁₇N₃O₆SC₂H₆₀

Molecular weight: 307.32 : 46.07

Ref: ST-EA-CP-G55012

Glutathione monoethyl ester

CAS: 118421-50-4

Glutathione monoethyl ester, a derivative of glutathione, can protect motor neuron cells (NSC-34) from TDP-43 pathology caused by mutations, which includes reducing aggregate formation, nuclear clearance, reactive oxygen species (ROS) production, and cell death.

Formula: C₁₂H₂₁N₃O₆S

Color and Shape: Solid

Molecular weight: 335.377

Ref: TM-T204308

Glutathione reduced ethyl ester

CAS: 118421-50-4

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Formula: C₁₂H₂₁N₃O₆S

Molecular weight: 335.38 g/mol

Ref: 3D-J-100171