CAS 118427-55-7: MK-886

Description: MK-886, with the CAS number 118427-55-7, is a chemical compound that serves as a selective inhibitor of the enzyme 5-lipoxygenase (5-LO), which is involved in the biosynthesis of leukotrienes. These inflammatory mediators play a significant role in various allergic and inflammatory conditions. MK-886 is primarily studied for its potential therapeutic applications in treating asthma and other inflammatory diseases. The compound is characterized by its ability to modulate immune responses and reduce inflammation by blocking the production of leukotrienes. In terms of its chemical structure, MK-886 features a unique arrangement of functional groups that contribute to its biological activity. It is typically administered in research settings to evaluate its efficacy and safety profile. As with many pharmacological agents, the understanding of MK-886's mechanism of action and its pharmacokinetics is crucial for its potential development into a therapeutic agent. However, further studies are necessary to fully elucidate its effects and possible side effects in clinical applications.

Formula: C₂₇H₃₃ClNNaO₂S

Synonyms:

• Mk 886 Sodium Salt
• 3-[Tert-Butylthio-1-(4-Chlorobenzyl)-5-Isopropyl-1H-Indol-2-Yl]-2,2-Dimethylpropionic Acid, Sodium Salt
• 1-[(4-Chlorophenyl)Methyl]-3-[(1,1-Dimethylethyl)Thio]-Alpha,Alpha-Dimethyl-5-(1-Methylethyl)-1H-Indole-2-Propanoic Acid, Sodium Salt
• 3-[3-Tert-Butylthio-1-(4-Chlorobenzyl)-5-Isopropyl-1H-Indol-2-Yl]-2,2-Dimethylpropionic Acid, Sodium
• 3-[1-(P-Chlorobenzyl)-5-(Isopropyl)-3-T-Butylthioindol-2-Yl]-2,2-Dimethylpropanoic Acid, Na
• 3-[1-(p-Chlorobenzyl)-5-(isopropyl)-3-t-butylthioindol-2-yl]-2,2-dimethylpropanoic acid,sodium
• 3-[3-Tert-Butylthio-1-(4-Chlorobenzyl)-5-Isopropyl-1H-Indol-2-Yl]-2,2-Dimethylpropionic Acid, Sodium Salt Hydrate

MK-886 sodium salt hydrate

CAS: 118427-55-7

• Formula: C₂₇H₃₃NO₂ClSNa·xH₂O
• Purity: ≥ 98.0%
• Color and Shape: White solid
• Molecular weight: 494.06 (anhydrous)

MK-886 Sodium Salt

CAS: 118427-55-7

• Formula: C₂₇H₃₃ClNO₂S·Na
• Color and Shape: Neat
• Molecular weight: 494.06

MK 886 sodium salt

CAS: 118427-55-7

Inhibitor of 5-lipoxygenase activating protein_x000D_

• Formula: C₂₇H₃₃ClNNaO₂S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 494.06 g/mol

MK-886 sodium salt

CAS: 118427-55-7

MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.

• Formula: C₂₇H₃₃ClNNaO₂S
• Color and Shape: Liquid
• Molecular weight: 494.06