CAS 1185049-09-5

Flumequine-13C3

Description:

Flumequine-13C3 is a labeled derivative of flumequine, an antibiotic belonging to the fluoroquinolone class, primarily used in veterinary medicine for the treatment of bacterial infections in animals. The "13C3" designation indicates that three carbon atoms in the molecule are isotopically labeled with carbon-13, a stable isotope of carbon, which is often used in research and analytical applications to trace metabolic pathways or quantify substances in biological samples. Flumequine itself exhibits broad-spectrum antibacterial activity by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. The incorporation of carbon-13 allows for enhanced detection and quantification using techniques such as nuclear magnetic resonance (NMR) spectroscopy or mass spectrometry. As with other fluoroquinolones, flumequine's use is subject to regulations due to concerns about antibiotic resistance and potential residues in food products. Overall, Flumequine-13C3 serves as a valuable tool in pharmacokinetic studies and environmental monitoring of antibiotic residues.

Formula: C₁₄H₁₂FNO₃

Synonyms:

• 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-1,2-13C2-2-carboxylic acid-13C
• Fantacin-13C3
• Flumequine-13C3
• 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid-13C3
• 9-Fluoro-6,7-dihydro-5-Methyl-1-oxo-
• Flumequine-(1,2,carboxy-13C3)
• Apurone-13C3
• R 802-13C3

Flumequine-13C3

CAS: 1185049-09-5

Formula: C₁₁₁₃C₃H₁₂FNO₃

Color and Shape: Off-White Solid

Molecular weight: 264.23

Ref: 4Z-F-067002

Flumequine 13C3

CAS: 1185049-09-5

Color and Shape: Neat

Ref: 04-C13718010

Flumequine 13C3 100 µg/mL in Acetonitrile

Controlled Product

CAS: 1185049-09-5

Formula: C₃C₁₁H₁₂FNO₃

Color and Shape: Single Solution

Molecular weight: 264.23

Ref: 04-A13718010AL-100

Flumequine-13C3

Controlled Product

CAS: 1185049-09-5

Applications Fluorinated quinolone antibacterial.
References Stilwell, G., et al.: Antimicrob. Agents Chemother., 7, 483 (1975), Rohlfing, S.R., et al.: J. Antimicrob. Chemother., 3, 615 (1977),

Formula: C₃C₁₁H₁₂FNO₃

Color and Shape: Off-White To Beige

Molecular weight: 264.23

Ref: TR-F445002