CAS 1185241-05-7

LANOCONAZOLE-D3

Description:

Lanoconazole-D3 is a synthetic antifungal agent that belongs to the class of azole compounds, specifically designed for the treatment of fungal infections. It is a deuterated derivative of lanoconazole, which means that it contains deuterium, a stable isotope of hydrogen, in its molecular structure. This modification can enhance the compound's stability and pharmacokinetic properties. Lanoconazole-D3 functions by inhibiting the enzyme lanosterol 14α-demethylase, which is crucial in the biosynthesis of ergosterol, an essential component of fungal cell membranes. By disrupting ergosterol synthesis, lanoconazole-D3 effectively compromises the integrity of the fungal cell membrane, leading to cell death. The compound is primarily used in research settings to study fungal infections and the mechanisms of antifungal resistance. Its unique isotopic labeling allows for advanced analytical techniques, such as mass spectrometry, to trace its metabolic pathways and interactions within biological systems. Overall, lanoconazole-D3 serves as a valuable tool in both clinical and laboratory investigations of antifungal therapies.

Formula: C₁₄H₇D₃ClN₃S₂

InChI: InChI=1S/C14H10ClN3S2/c15-11-4-2-1-3-10(11)13-8-19-14(20-13)12(7-16)18-6-5-17-9-18/h1-6,9,13H,8H2/i5D,6D,9D

InChI key: InChIKey=ZRTQSJFIDWNVJW-DINNLGBQSA-N

SMILES: C(C#N)(=C1SC(CS1)C2=C(Cl)C=CC=C2)N3C(=C(N=C3[2H])[2H])[2H]

Synonyms:

• Astat-d
• Astat-d3
• TJN-318-d3
• NND-318-d3
• Latoconazole-d3
• LANOCONAZOLE-D3
• (E)-(+/-)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-d3-1-acetonitrile

Lanoconazole-d3

Controlled Product

CAS: 1185241-05-7

Formula: C₁₄D₃H₇ClN₃S₂

Color and Shape: Neat

Molecular weight: 322.851

Ref: TR-L174502