CAS 1186048-34-9

6-Bromobetamethasone dipropionate

Description:

6-Bromobetamethasone dipropionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a derivative of betamethasone, characterized by the presence of a bromine atom at the 6-position of the steroid nucleus. This modification enhances its potency and efficacy in treating various inflammatory conditions. The dipropionate ester form allows for improved solubility and prolonged action, making it suitable for topical applications. The compound is typically used in dermatological formulations to manage skin disorders such as eczema, psoriasis, and dermatitis. Its mechanism of action involves the inhibition of inflammatory mediators and modulation of immune responses. As with other corticosteroids, potential side effects may include skin thinning, local irritation, and systemic absorption leading to more widespread effects. Proper usage guidelines and dosage are essential to minimize adverse effects while maximizing therapeutic benefits. Overall, 6-Bromobetamethasone dipropionate is a valuable agent in the pharmacological management of inflammatory skin diseases.

Formula: C₂₈H₃₆BrFO₇

InChI: InChI=1S/C28H36BrFO7/c1-6-23(34)36-14-22(33)28(37-24(35)7-2)15(3)10-17-18-12-20(29)19-11-16(31)8-9-25(19,4)27(18,30)21(32)13-26(17,28)5/h8-9,11,15,17-18,20-21,32H,6-7,10,12-14H2,1-5H3/t15-,17-,18-,20?,21-,25-,26-,27-,28-/m0/s1

InChI key: InChIKey=IWDYBQRUEBZMDR-QTSRRJNPSA-N

SMILES: C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(C(Br)C3)=CC(=O)C=C4)[H])[H]

Synonyms:

• (11β,16β)-6-Bromo-9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 6-bromo-9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16β)-
• 6-Bromobetamethasone dipropionate

6-Bromo-Betamethasone-17,21-Dipropionate (Mixture of Diastereomers)

CAS: 1186048-34-9

Formula: C₂₈H₃₆BrFO₇

Molecular weight: 583.49

Ref: 4Z-B-065159

6-Bromo-betamethasone-17,21-dipropionate

CAS: 1186048-34-9

Formula: C₂₈H₃₆BrFO₇

Color and Shape: White To Off-White Solid

Molecular weight: 583.49

Ref: 4Z-B-065013

6-Bromo-betamethasone 17,21-Dipropionate

Controlled Product

CAS: 1186048-34-9

Stability Hygroscopic
Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.
References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)

Formula: C₂₈H₃₆BrFO₇

Color and Shape: Neat

Molecular weight: 583.48

Ref: TR-B680330

6-Bromo-betamethasone 17,21-dipropionate

Controlled Product

CAS: 1186048-34-9

6-Bromo-betamethasone 17,21-dipropionate is a chemical intermediate that can be used to synthesize a wide variety of compounds. It has a high quality and is versatile. 6-Bromo-betamethasone 17,21-dipropionate is a fine chemical with many uses in the research and development industry. This compound is also useful for the production of pharmaceuticals, pesticides, antibiotics, and other organic compounds.

Formula: C₂₈H₃₆BrFO₇

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 583.48 g/mol

Ref: 3D-FB45448

6-Bromo-betamethasone-17,21-dipropionate

CAS: 1186048-34-9

Formula: C₂₈H₃₆BrFO₇

Molecular weight: 583.49

Ref: ST-EA-CP-B25145