HL001, identified by its CAS number 1186371-31-2, is a chemical compound that has garnered attention in various research fields, particularly in medicinal chemistry. While specific details about its physical and chemical properties may vary, compounds of this nature typically exhibit characteristics such as a defined molecular structure, solubility in organic solvents, and potential biological activity. HL001 may be studied for its interactions with biological targets, which could include enzyme inhibition or receptor modulation. Its synthesis often involves multi-step organic reactions, and it may be characterized using techniques such as NMR spectroscopy, mass spectrometry, and chromatography. The compound's safety profile, including toxicity and environmental impact, is also crucial for its application in research or potential therapeutic uses. As with any chemical substance, proper handling and storage protocols should be followed to ensure safety and compliance with regulatory standards. Further research and data are essential to fully understand the implications of HL001 in scientific applications.

HL001

(HL 001)

1186371-31-2: HL001, identified by its CAS number 1186371-31-2, is a chemical compound that has garnered attention in various research fields, particularly in medicinal chemistry. While specific details about its physical and chemical properties may vary, compounds of this nature typically exhibit characteristics such as a defined molecular structure, solubility in organic solvents, and potential biological activity. HL001 may be studied for its interactions with biological targets, which could include enzyme inhibition or receptor modulation. Its synthesis often involves multi-step organic reactions, and it may be characterized using techniques such as NMR spectroscopy, mass spectrometry, and chromatography. The compound's safety profile, including toxicity and environmental impact, is also crucial for its application in research or potential therapeutic uses. As with any chemical substance, proper handling and storage protocols should be followed to ensure safety and compliance with regulatory standards. Further research and data are essential to fully understand the implications of HL001 in scientific applications.

<p>HL001 is an orally active small molecule inhibitor of cyclophilin A (CypA) and a receptor antagonist of lysophosphatidic acid 1 (LPA1). It induces cell cycle arrest and apoptosis in tumor cells via p53. By downregulating G3BP1, HL001 promotes reactive oxygen species production and DNA damage to stabilize p53. It disrupts the interaction between MDM2 and p53-72R in a CypA-dependent manner. HL001 exhibits antitumor activity and can also be used in research on pulmonary fibrosis.</p>

CAS 1186371-31-2

HL001 (HL 001)

HL001

Ref: TM-T204158