CymitQuimica logo

CAS 1186404-60-3

:

5-Chloro-6-(trifluoromethyl)-1H-indole

Description:
5-Chloro-6-(trifluoromethyl)-1H-indole is a chemical compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a chlorine atom at the 5-position and a trifluoromethyl group at the 6-position significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and is known for its potential applications in pharmaceuticals and agrochemicals due to its unique electronic and steric properties. The trifluoromethyl group enhances lipophilicity and metabolic stability, making it a valuable moiety in drug design. Additionally, the chlorine substituent can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The compound's molecular structure contributes to its biological activity, and it may exhibit interesting pharmacological effects, although specific biological data would depend on empirical studies. As with many halogenated compounds, safety and handling precautions are essential due to potential toxicity and environmental impact.
Formula:C9H5ClF3N
InChI:InChI=1S/C9H5ClF3N/c10-7-3-5-1-2-14-8(5)4-6(7)9(11,12)13/h1-4,14H
InChI key:InChIKey=VLLFFZSKKBGBRG-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C=1C=C2C(=CC1Cl)C=CN2
Synonyms:
  • 5-Chloro-6-(trifluoromethyl)-1H-indole
  • 1H-Indole, 5-chloro-6-(trifluoromethyl)-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.