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CAS 1187-00-4

:

D-Mannitol busulfan

Description:
D-Mannitol busulfan, with the CAS number 1187-00-4, is a chemical compound that combines the sugar alcohol D-mannitol with the alkylating agent busulfan. D-mannitol is known for its use as a diuretic and in pharmaceutical formulations, while busulfan is primarily utilized in chemotherapy for its ability to inhibit DNA synthesis in cancer cells. The combination of these two components may enhance the therapeutic efficacy of busulfan while potentially mitigating some of its side effects, such as myelosuppression. D-Mannitol busulfan is typically characterized by its solid state at room temperature, and it is soluble in water, which is advantageous for intravenous administration. The compound's mechanism of action involves the alkylation of DNA, leading to cross-linking and subsequent cell death, particularly in rapidly dividing cells. As with many chemotherapeutic agents, careful consideration of dosing and monitoring for adverse effects is essential in clinical settings. Overall, D-mannitol busulfan represents a significant area of interest in cancer treatment research.
Formula:C8H18O10S2
InChI:InChI=1S/C8H18O10S2/c1-19(13,14)17-3-5(9)7(11)8(12)6(10)4-18-20(2,15)16/h5-12H,3-4H2,1-2H3/t5-,6-,7-,8-/m1/s1
InChI key:InChIKey=ODOISJJCWUVNDJ-WCTZXXKLSA-N
SMILES:[C@H]([C@@H]([C@@H](COS(C)(=O)=O)O)O)([C@@H](COS(C)(=O)=O)O)O
Synonyms:
  • 1,6-Bis(O-methylsulfonyl)-D-mannitol
  • 1,6-Bis(methanesulfonyl)-<span class="text-smallcaps">D</span>-mannitol
  • 1,6-Bis(methanesulfonyl)-D-mannitol
  • 1,6-Bis-0-methylsulfonyl-D-mannitol
  • 1,6-Dimesyl-<span class="text-smallcaps">D</span>-mannitol
  • 1,6-Dimesyl-D-mannitol
  • 1,6-Dimethane-sulfonoxy-D-mannitol
  • 1,6-Dimethanesulfonate-D-mannitol
  • 1,6-Dimethanesulfonoxy-1,6-dideoxy-D-mannitol
  • 1,6-Dimethanesulfonyl-<span class="text-smallcaps">D</span>-mannitol
  • See more synonyms
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Found 2 products.
  • Mannitol myleran
    Targetmol
    + Info

    Mannitol myleran

    CAS:
    Mannitol myleran is a reagent used in the preparation of pharmaceutical compounds for tumor diagnosis and treatment.
    Formula:C8H18O10S2
    Color and Shape:Solid
    Molecular weight:338.34

    Ref: TM-T33213

  • 1,6-Dimethanesulfonate-D-mannitol
    TRC
    + Info

    1,6-Dimethanesulfonate-D-mannitol

    Controlled Product
    CAS:
    Formula:C8H18O10S2
    Color and Shape:Neat
    Molecular weight:338.353

    Ref: TR-D478945

    1g
    2,058.00€