CAS 118745-63-4

2-FLUORO-4-METHYLBENZYL BROMIDE

Description:

2-Fluoro-4-methylbenzyl bromide is an organic compound characterized by its aromatic structure, which includes a fluorine atom and a bromine atom attached to a benzyl group. The presence of the fluorine atom at the ortho position relative to the methyl group and the bromine atom at the benzyl position contributes to its reactivity and potential applications in organic synthesis. This compound is typically a colorless to pale yellow liquid, exhibiting moderate volatility and solubility in organic solvents. Its molecular structure suggests that it may participate in nucleophilic substitution reactions, making it useful in the synthesis of various pharmaceuticals and agrochemicals. Additionally, the presence of both halogen substituents can influence its electronic properties, potentially affecting its reactivity and interactions with other chemical species. Safety precautions should be taken when handling this compound, as it may pose health risks due to its halogenated nature. Overall, 2-fluoro-4-methylbenzyl bromide is a valuable intermediate in the field of synthetic organic chemistry.

Formula: C₈H₈BrF

InChI: InChI=1/C8H8BrF/c1-6-2-3-7(5-9)8(10)4-6/h2-4H,5H2,1H3

SMILES: Cc1ccc(CBr)c(c1)F

Synonyms:

• 1-(Bromomethyl)-2-fluoro-4-methylbenzene
• Benzene, 1-(Bromomethyl)-2-Fluoro-4-Methyl-
• Fr C1 F1E
• 2-Fluoro-4-methylbenzyl bromide

2-Fluoro-4-methylbenzyl bromide

CAS: 118745-63-4

Formula: C₈H₈BrF

Purity: 98%

Color and Shape: Liquid

Molecular weight: 203.0515

Ref: IN-DA003H9K

2-Fluoro-4-methylbenzyl bromide

CAS: 118745-63-4

2-Fluoro-4-methylbenzyl bromide

Formula: C₈H₈BrF

Purity: ≥95%

Color and Shape: Colourless Liquid

Molecular weight: 203.05g/mol

Ref: 54-PC5936

2-Fluoro-4-methylbenzyl bromide

CAS: 118745-63-4

Formula: C₈H₈BrF

Purity: 98%

Color and Shape: Liquid

Molecular weight: 203.054

Ref: 10-F342355

2-Fluoro-4-methylbenzyl Bromide

Controlled Product

CAS: 118745-63-4

Applications 2-Fluoro-4-methylbenzyl Bromide is used as a reagent in the synthesis of tetrahydrocarboline derivatives which can serve as inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2). 2-Fluoro-4-methylbenzyl Bromide is also used as a reagent in the preparation of benzamide derivatives as angiogenesis inhibitors for treatment of cancer, metastasis.
References Ohata, A., et al.: PCT Int. Appl. WO 2012005227 A1 20120112. Jan 12, 2012; Koyano, H., et al.: PCT Int. Appl. WO 2005063689 A1 20050714. Jul 14, 2005

Formula: C₈H₈BrF

Color and Shape: Neat

Molecular weight: 203.05

Ref: TR-F593620