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Baricitinib

CAS 1187594-09-7: Baricitinib

Description:Baricitinib is a small molecule drug primarily used for the treatment of moderate to severe rheumatoid arthritis. It functions as a selective inhibitor of Janus kinase (JAK) enzymes, specifically JAK1 and JAK2, which play a crucial role in the signaling pathways of various cytokines involved in inflammatory processes. The chemical formula of Baricitinib is C16H17N3O2, and it has a molecular weight of approximately 285.33 g/mol. The substance appears as a white to off-white crystalline powder and is soluble in dimethyl sulfoxide (DMSO) and slightly soluble in water. Baricitinib is administered orally and has been shown to reduce the signs and symptoms of rheumatoid arthritis by modulating the immune response. Its pharmacokinetics indicate a relatively long half-life, allowing for once-daily dosing. As with any medication, potential side effects include increased risk of infections, liver enzyme elevations, and changes in blood cell counts, necessitating monitoring during treatment.

Formula:C16H17N7O2S

InChI:InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)

InChI key:InChIKey=XUZMWHLSFXCVMG-UHFFFAOYSA-N

SMILES:N#CCC1(N2N=CC(=C2)C=3N=CN=C4NC=CC43)CN(C1)S(=O)(=O)CC

  • Synonyms:
  • 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile
  • 2-(3-(4-(3H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
  • 2-(3-(4-(7H-Pyrrolo[2,3-D]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
  • 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-
  • Incb 028050
  • Incb 28050
  • Incb028050
  • Ly 3009104
  • Ly3009104
  • Olumiant
  • See more synonyms
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Found 10 products.

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Ref: IN-DA003A5U

1g63.00 €
5g158.00 €
10g203.00 €
25g595.00 €
100mg30.00 €
250mg33.00 €
Estimated delivery in United States, on Tuesday 4 Mar 2025
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Baricitinib

CAS:1187594-09-7

Ref: 4Z-B-154001

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Baricitinib

Controlled Product
CAS:1187594-09-7

Ref: 86-MM3905.00-0250

250mg1,107.00 €
Estimated delivery in United States, on Friday 7 Mar 2025
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Baricitinib

CAS:1187594-09-7

Ref: 7W-GW9910

10mg79.00 €
50mg123.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Baricitinib

CAS:1187594-09-7

Ref: TM-T2485

5mg50.00 €
10mg73.00 €
25mg90.00 €
50mg115.00 €
100mg144.00 €
200mg188.00 €
500mg311.00 €
1mL*10mM (DMSO)69.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Baricitinib

Controlled Product
CAS:1187594-09-7

Ref: TR-B118690

10mg528.00 €
50mg1,583.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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Ref: 10-F468368

1g122.00 €
5g177.00 €
250mg91.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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Baricitinib - Bio-X ™

CAS:1187594-09-7

Ref: 3D-BB184033

10mg147.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Baricitinib

CAS:1187594-09-7

Ref: 3D-FE30357

1g743.00 €
2g990.00 €
5g1,165.00 €
250mg365.00 €
500mg520.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Baricitinib Azetidine-d4

Controlled Product
CAS:1187594-09-7

Ref: TR-B118694

50mg24,466.00 €
Estimated delivery in United States, on Monday 14 Apr 2025
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