CAS 1187595-84-1: Baricitinib phosphate salt

Description: Baricitinib phosphate salt is a pharmaceutical compound primarily used as a treatment for rheumatoid arthritis and has gained attention for its potential in treating COVID-19. It is a selective inhibitor of Janus kinase (JAK) enzymes, which play a crucial role in the signaling pathways of various cytokines involved in inflammatory processes. The compound is characterized by its ability to modulate immune responses, thereby reducing inflammation and joint damage in autoimmune conditions. Baricitinib phosphate salt is typically administered orally and is known for its relatively favorable pharmacokinetic profile, including good absorption and distribution in the body. Its chemical structure includes a phosphate group, which enhances its solubility and bioavailability. Safety and efficacy profiles have been established through clinical trials, although potential side effects may include increased risk of infections and changes in blood cell counts. Overall, Baricitinib phosphate salt represents a significant advancement in targeted therapies for inflammatory diseases.

Synonyms:

• [1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile phosphate
• 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile phosphate

Baricitinib phosphate salt

CAS: 1187595-84-1

• Formula: C₁₆H₂₀N₇O₆PS
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 469.4121

Baricitinib phosphate

CAS: 1187595-84-1

Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.

• Formula: C₁₆H₂₀N₇O₆PS
• Purity: 98.87% - 99.68%
• Color and Shape: Solid
• Molecular weight: 469.41

Baricitinib phosphate

CAS: 1187595-84-1

Baricitinib phosphate is a drug that belongs to the class of tyrosine kinase inhibitors. It …

• Formula: C₁₆H₂₀N₇O₆PS
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 469.41 g/mol