CAS 118812-69-4

Ularitide

Description:

Ularitide, with the CAS number 118812-69-4, is a synthetic peptide that has been investigated primarily for its potential therapeutic applications in cardiovascular medicine. It is a member of the natriuretic peptide family, which plays a crucial role in regulating blood pressure and fluid balance. Ularitide functions as a vasodilator, promoting the relaxation of blood vessels and thereby reducing cardiac preload and afterload. This mechanism can be beneficial in treating conditions such as acute heart failure. The substance is characterized by its ability to enhance renal excretion of sodium and water, contributing to its diuretic effects. Ularitide has been studied in clinical settings, showing promise in improving hemodynamic parameters and overall patient outcomes. Its pharmacokinetics and safety profile are important considerations in its development as a therapeutic agent. As with any peptide-based drug, stability, delivery methods, and potential immunogenicity are critical factors influencing its clinical application.

Formula: C₁₄₅H₂₃₄N₅₂O₄₄S₃

Synonyms:

• Atrial natriuretic factor prohormone (95-126)
• L-Threonyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic (11->27)-disulfide
• Ularitide [INN]
• L-Threonyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic (11-27)-disulfide
• UNII-740Y5J48Z8

Ularitide

CAS: 118812-69-4

Ularitide is a 32-amino acid peptide from ANP prohormone, resistant to dog kidney cortex peptidase.

Formula: C₁₄₅H₂₃₄N₅₂O₄₄S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 3505.97

Ref: TM-TP2357