CAS 1188263-52-6

1-Propanone, 1-[2-(3-amino-2-hydroxypropoxy)phenyl]-3-phenyl-, hydrochloride (1:1)

Description:

1-Propanone, 1-[2-(3-amino-2-hydroxypropoxy)phenyl]-3-phenyl-, hydrochloride (1:1), with CAS number 1188263-52-6, is a chemical compound characterized by its complex structure, which includes a propanone moiety and a phenyl group. This compound features an amino group and a hydroxypropoxy substituent, contributing to its potential biological activity. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, enhancing its utility in various applications, particularly in pharmaceuticals. The presence of the amino and hydroxy groups suggests potential for hydrogen bonding, which may influence its interaction with biological targets. This compound may exhibit properties such as moderate to high polarity, and its stability can be affected by pH and temperature. Its specific applications and effects would depend on further studies, particularly in the context of medicinal chemistry, where such compounds are often explored for therapeutic potential. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₁₈H₂₂ClNO₃

InChI: InChI=1S/C18H21NO3.ClH/c19-12-15(20)13-22-18-9-5-4-8-16(18)17(21)11-10-14-6-2-1-3-7-14;/h1-9,15,20H,10-13,19H2;1H

InChI key: InChIKey=PJHPAIZGMQFXFZ-UHFFFAOYSA-N

SMILES: C(CCC1=CC=CC=C1)(=O)C2=C(OCC(CN)O)C=CC=C2.Cl

Synonyms:

• 1-Propanone, 1-[2-(3-amino-2-hydroxypropoxy)phenyl]-3-phenyl-, hydrochloride (1:1)
• Propafenone N-Despropyl HCl
• Propafenone Impurity 12(N-Despropyl Propafenone HCl)
• Propafenone Impurity 13
• N-Dealkyl propafenone Oxalate Salt
• N-Despropyl Propafenone Hydrochloride

N-Despropyl Propafenone Hydrochloride (2'-(2-Hydroxy-3-aminopropoxy)-3-phenylpropiophenone hydrochloride)

CAS: 1188263-52-6

Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters, salts thereof, nesoi

Formula: C₁₈H₂₂ClNO₃

Color and Shape: Brown Liquid Viscous

Molecular weight: 335.12882

Ref: 45-1A08660

N-Despropyl Propafenone HCl

CAS: 1188263-52-6

Formula: C₁₈H₂₁NO₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 299.37 36.46

Ref: 4Z-P-152

4-Hydroxy Propafenone

CAS: 1188263-52-6

Formula: C₂₁H₂₇NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 357.45

Ref: 4Z-P-1526

N-Despropyl Propafenone Hydrochloride

Controlled Product

CAS: 1188263-52-6

Stability Hygroscopic
Applications N-Despropyl Propafenone Hydrochloride is a metabolite of Propafenone (P757500), a sodium channel blocker. Antiarrhythmic (class IC).
References Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983); Bryson, H. M., et al.:Drugs, 45, 85 (1993); Rae, A. P., et al.: Am. J. Cardiol., 82, 59N (1998)

Formula: C₁₈H₂₂ClNO₃

Color and Shape: Neat

Molecular weight: 335.83

Ref: TR-D288290

N-Despropyl propafenone hydrochloride

CAS: 1188263-52-6

N-Despropyl propafenone hydrochloride is an analytical standard used in drug development and research. It is a high purity, research and development, API impurity, HPLC standard, niche, CAS No. 1188263-52-6, drug product, Impurity standard and Metabolite. It is also a Custom synthesis and Natural or Synthetic drug product.

Formula: C₁₈H₂₂ClNO₃

Purity: Min. 95%

Molecular weight: 335.8 g/mol

Ref: 3D-NXB26352