CAS 118850-78-5

N-T-boc-ala-gly-pro-arg 7-amido-4-*methylcoumarin

Description:

N-T-boc-ala-gly-pro-arg 7-amido-4-methylcoumarin is a synthetic compound often utilized in biochemical research, particularly in the study of proteolytic enzymes and peptide interactions. This compound features a protective tert-butyloxycarbonyl (Boc) group, which is commonly used to shield amino groups during peptide synthesis. The structure includes a sequence of amino acids—alanine (Ala), glycine (Gly), proline (Pro), and arginine (Arg)—which contributes to its biological activity and specificity. The 7-amido-4-methylcoumarin moiety serves as a fluorescent reporter group, making it useful for monitoring enzymatic activity through fluorescence assays. The compound's characteristics include its solubility in organic solvents, stability under standard laboratory conditions, and its potential to undergo hydrolysis or enzymatic cleavage, releasing the amino acids and the fluorescent coumarin. This makes it a valuable tool in studying enzyme kinetics and substrate specificity in various biological systems.

Formula: C₃₁H₄₄N₈O₈·HCl

Synonyms:

• Boc-Ala-Gly-Pro-Arg-AMC . HCl

Boc-Ala-Gly-Pro-Arg-AMC

CAS: 118850-78-5

Boc-Ala-Gly-Pro-Arg-AMC is a research tool that belongs to the ligand category. It is a cell biology reagent that can be used as an activator or inhibitor of various ion channels, including potassium and sodium channels. Boc-Ala-Gly-Pro-Arg-AMC has been shown to inhibit the binding of antibodies to their antigen and has been used in pharmacology studies involving peptides. This product is also used for research in cell biology, antibody production, protein interactions, and pharmacology.

Formula: C₃₁H₄₄N₈O₈

Purity: Min. 95%

Molecular weight: 656.73 g/mol

Ref: 3D-MAR-3144-V