CAS 118876-58-7

1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo[f]quinoxaline-7-sulfonamide

Description:

1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo[f]quinoxaline-7-sulfonamide, with the CAS number 118876-58-7, is a synthetic organic compound that belongs to the class of quinoxaline derivatives. This compound features a bicyclic structure characterized by a fused benzene and quinoxaline ring system, which contributes to its unique chemical properties. The presence of a nitro group and a sulfonamide functional group enhances its reactivity and solubility in various solvents. It is often studied for its potential biological activities, including antimicrobial and anticancer properties. The compound's dioxo substituents may also play a role in its interaction with biological targets, making it of interest in medicinal chemistry. Additionally, its structural complexity allows for various modifications, which can lead to the development of analogs with improved efficacy or selectivity. Overall, this compound exemplifies the intricate relationship between molecular structure and biological activity, making it a valuable subject for further research in pharmaceutical applications.

Formula: C₁₂H₈N₄O₆S

InChI: InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)

InChI key: InChIKey=UQNAFPHGVPVTAL-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C=1C=2C(=C3C(=CC2N(=O)=O)NC(=O)C(=O)N3)C=CC1

Synonyms:

• 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo(f)quinoxaline-8-sulfonamide
• 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo[f]quinoxaline-7-sulfonamide
• 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline
• 6-Nitro-2,3-Dioxo-1,2,3,4-Tetrahydrobenzo[F]Quinoxaline-7-Sulfonamide
• 6-Nitro-2,3-Dioxo-2,3-Dihydrobenzo[F]Quinoxaline-7-Sulfonamide
• 6-Nitro-7-sulfamoylbenzo(f)quinoxaline-2,3-dione
• Benzo(f)quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-
• Disodium 6-Nitro-7-Sulfamoylbenzo[F]Quinoxaline-2,3-Diolate
• Fg 9202
• Nbqx
• 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt
• NBQX HYDRATE
• FG 9202 DISODIUM
• NBQX DISODIUM (FG 9202) NEUROPROTECTIVE GLUTA
• 2,3-Dihydroxy-6-nitrobenzo[f]quinoxaline-7-sulfonamide
• 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrate
• 6-NITRO-7-SULFAMOYLBENZO[F]QUINOXALINE-2,3-DIONE, DISODIUM SALT
• 6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE-2,3-DIONE
• 2,3-DIOXO-6-NITRO-1,2,3,4-TETRAHYDROBENZO[F]QUINOXALINE-7-SULFONAMIDE DISODIUM SALT
• 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide hydrate
• 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline
• NBQX DISODIUM SALT
• NBQX disodium salt hydrate
• 1,2,3,4-TETRAHYDRO-6-NITRO-2,3-DIOXO-BENZO[F]QUINOXALINE-7-SULFONAMIDE
• 2,3-DIOXO-6-NITRO-1,2,3,4-TETRAHYDROBENZO[F]QUINOXALINE-7-SULFONAMIDE
• 1,2,3,4-TETRAHYDRO-6-NITRO-2,3-DIOXO-BENZO[F]QUINOXALINE-7-SULFONAMIDE DISODIUM
• 6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE-2,3-DIONE 2NA
• FG 9202, 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide hydrate
• FG 9202 disodium salt hydrate
• 2,3-DIHYDROXY-6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE
• 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
• 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3(1H,4H)-dione
• FG 9202 hydrate disodium salt, 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide hydrate disodium salt
• NBQX hydrate disodium salt
• 2,3-DIHYDROXY-6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE 2NA
• 2,3-Doxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline

NBQX

CAS: 118876-58-7

Formula: C₁₂H₈N₄O₆S

Purity: >92.0%(HPLC)(qNMR)

Molecular weight: 336.28

Ref: 3B-N1287

NBQX

CAS: 118876-58-7

NBQX

Formula: C₁₂H₈N₄O₆S

Purity: >99%

Molecular weight: 336.28

Ref: 54-OR1023954

1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo[f]quinoxaline-7-sulfonamide

CAS: 118876-58-7

Formula: C₁₂H₈N₄O₆S

Purity: 97%

Color and Shape: Solid

Molecular weight: 336.2801

Ref: IN-DA008RLB

NBQX

CAS: 118876-58-7

NBQX

Formula: C₁₂H₈N₄O₆S

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 336.28

Ref: 54-BUP12815

NBQX disodium salt

CAS: 118876-58-7

Formula: C₁₂H₈N₄O₆S·xH₂O

Molecular weight: 380.3

Ref: 7W-GM8007

6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-Dione

CAS: 118876-58-7

Stability Freezer at -20°C
Applications A potent and discriminating antagonist for AMPA binding sites. This compound has neuroprotective properties.
References HonorÈ, T., et al.: Science, 241, 701 (1988), Gill, et al.: Brain Res., 580, 35 (1992), Pook, et al.: Br. J. Pharmacol., 108, 179 (1993)

Formula: C₁₂H₈N₄O₆S

Color and Shape: Neat

Molecular weight: 336.28

Ref: TR-N550000

NBQX

CAS: 118876-58-7

NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.

Formula: C₁₂H₈N₄O₆S

Purity: 97.66% - 99.93%

Color and Shape: Solid

Molecular weight: 336.28

Ref: TM-T4113

NBQX

CAS: 118876-58-7

Competitive antagonist of ionotropic glutamate receptors of AMPA and kainate subfamilies. Reported anti-convulsant activity in seizures models induced by electrostimulation, drugs or genetic predisposition. Pro-convulsant effects in Theiler's murine encephalomyelitis virus-induced (TMEV) seizure model.

Formula: C₁₂H₈N₄O₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 336.28 g/mol

Ref: 3D-BN167535

NBQX

CAS: 118876-58-7

6-Nitro-2,3-dioxo-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide

Formula: C₁₂H₈N₄O₆S

Purity: 97%

Molecular weight: 336.28

Ref: IN-DG00790745

NBQX

CAS: 118876-58-7

M02152 - NBQX

Formula: C₁₂H₈N₄O₆S

Purity: 97%

Color and Shape: Solid

Molecular weight: 336.28

Ref: 10-M02152