CAS 1189467-36-4

Nalidixic Acid-d5

Description:

Nalidixic Acid-d5 is a deuterated derivative of nalidixic acid, a synthetic antibiotic belonging to the quinolone class. It is primarily used in research and analytical applications, particularly in studies involving drug metabolism and pharmacokinetics. The deuteration, indicated by the "d5" in its name, refers to the substitution of five hydrogen atoms with deuterium, a stable isotope of hydrogen. This modification enhances the compound's stability and alters its mass, making it useful in mass spectrometry and NMR spectroscopy for tracking and quantifying the substance in biological samples. Nalidixic Acid-d5 retains the core structural features of nalidixic acid, including its carboxylic acid group and quinolone ring, which are essential for its antibacterial activity. However, the presence of deuterium can influence its solubility and interaction with biological systems. Overall, Nalidixic Acid-d5 serves as a valuable tool in pharmacological research, allowing scientists to investigate the behavior of nalidixic acid in various environments while minimizing interference from naturally occurring isotopes.

Formula: C₁₂H₁₂N₂O₃

Synonyms:

• 1,4-Dihydro-1-(ethyl-d5)-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid
• Dixiben-d5
• Nelidix-d5-
• Cybis-d5
• Nalidixic acid-(ethyl-d5)
• Nalidixic Acid-d5
• Betaxina-d5
• Win 18320-d5
• Wintomylon-d5
• 1,4-Dihydro-1-(ethyl-d5)-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid
• NegGram-d5
• Eucistin-d5

Nalidixic acid D5 (ethyl D5)

CAS: 1189467-36-4

Color and Shape: Neat

Ref: 04-C15412001

Nalidixic Acid-d5

Controlled Product

CAS: 1189467-36-4

Applications Antibacterial.
References Bourguignon, G.J., et al.: Antimicrob. Agents Chemother., 4, 479 (1973), Grubb, P.E., et al.: Anal. Profiles Drug Subs., 8, 371 (1979), Wright, H.T., et al.: Science, 213, 455 (1981),

Formula: C₁₂₂H₅H₇N₂O₃

Color and Shape: Light Yellow To Light Green

Molecular weight: 237.27

Ref: TR-N275602

Nalidixic acid-d5

Controlled Product

CAS: 1189467-36-4

Nalidixic acid-d5 is a research tool that can be used in the study of ion channels and receptors. It is an activator ligand that binds to its receptor, leading to a conformational change. Nalidixic acid-d5 may also inhibit the activity of a protein by binding to it, blocking access to an active site or substrate. This product has been shown to have pharmacological properties and can be used in the study of peptides.

Formula: C₁₂H₇D₅N₂O₃

Purity: Min. 95%

Molecular weight: 237.27 g/mol

Ref: 3D-PXB46736