CAS 1189469-46-2
:Loperamide D6
Description:
Loperamide D6 is a deuterated analog of loperamide, which is primarily used as an antidiarrheal medication. The deuteration refers to the substitution of hydrogen atoms with deuterium, a heavier isotope of hydrogen, which can enhance the stability and metabolic tracking of the compound in biological studies. Loperamide itself acts on the μ-opioid receptors in the gut, reducing gastrointestinal motility and prolonging transit time, thereby alleviating diarrhea. The chemical structure of Loperamide D6 retains the core features of loperamide, including its aromatic rings and amide functional group, while the presence of deuterium may influence its pharmacokinetics and dynamics. This compound is often utilized in research settings to study drug metabolism and pharmacological effects without the interference of natural isotopes. As with any chemical substance, safety and handling precautions should be observed, and its use should be guided by appropriate regulatory standards.
Formula:C29H28Cl2D6N2O2
Synonyms:- LOPERAMIDE-D6
- [2H6]-Loperamide hydrochloride
- [2H6]-Loperamide
- Loperamide-d6 HCl (dimethyl-d6)
- Loperamide hydrochloride salt
- 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-N,N-bis(trideuteriomethyl)butanamide hydrochloride
- R-18553 D6 hydrochloride
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Found 4 products.
Loperamide-d6 hydrochloride
CAS:Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.Formula:C29H34Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:519.54Loperamide-d6 Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Loperamide, which is used as an antidiarrheal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stokbroekx, et al.: J. Med. Chem., 1, 782 (1973), Carter, J.E., et al.: Anal. Profiles Drug Subs., 19, 341 (1990),<br></p>Formula:C29H27D6ClN2O2·HClColor and Shape:WhiteMolecular weight:519.54
