Acebutolol-D5 is a deuterated form of acebutolol, a beta-blocker primarily used to manage hypertension and certain heart conditions. As a deuterated compound, Acebutolol-D5 contains five deuterium atoms, which are isotopes of hydrogen, replacing regular hydrogen atoms in the molecular structure. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful in research applications, particularly in studies involving drug metabolism and pharmacodynamics. The presence of deuterium can also aid in distinguishing the compound in analytical techniques such as mass spectrometry. Acebutolol itself is characterized by its ability to selectively block beta-1 adrenergic receptors, leading to decreased heart rate and myocardial contractility. The deuterated version may exhibit similar therapeutic effects, but its unique isotopic composition allows for more precise tracking in biological systems. Overall, Acebutolol-D5 serves as a valuable tool in pharmacological research, providing insights into the behavior of beta-blockers in clinical settings.

Acebutolol-D5

1189500-68-2: Acebutolol-D5 is a deuterated form of acebutolol, a beta-blocker primarily used to manage hypertension and certain heart conditions. As a deuterated compound, Acebutolol-D5 contains five deuterium atoms, which are isotopes of hydrogen, replacing regular hydrogen atoms in the molecular structure. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful in research applications, particularly in studies involving drug metabolism and pharmacodynamics. The presence of deuterium can also aid in distinguishing the compound in analytical techniques such as mass spectrometry. Acebutolol itself is characterized by its ability to selectively block beta-1 adrenergic receptors, leading to decreased heart rate and myocardial contractility. The deuterated version may exhibit similar therapeutic effects, but its unique isotopic composition allows for more precise tracking in biological systems. Overall, Acebutolol-D5 serves as a valuable tool in pharmacological research, providing insights into the behavior of beta-blockers in clinical settings.

<p>Applications Cardioselective β-adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).<br>References Cuthbert, O.A., et al.: Br. J. Pharmacol., 43, 639 (1971), Singh, B.N., et al.: Drugs, 29, 531 (1985), Foster, R.T., et al.: Anal. Profiles Drug Subs., 19, 1 (1990),<br></p>

CAS 1189500-68-2

Acebutolol-D5

Acebutolol-d5

Ref: TR-A123802