CAS 1189710-20-0

Pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide, 5-butyl-N2-(3-chloro-4-methylphenyl)-N6-cyclopentyl-4,5,6,7-tetrahydro-6-methyl-4-oxo-

Description:

Pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide, 5-butyl-N2-(3-chloro-4-methylphenyl)-N6-cyclopentyl-4,5,6,7-tetrahydro-6-methyl-4-oxo- is a complex organic compound characterized by its unique bicyclic structure, which incorporates both pyrazole and pyrazine moieties. This compound features multiple functional groups, including carboxamide and various alkyl and aryl substituents, which contribute to its chemical reactivity and potential biological activity. The presence of a butyl group and a cyclopentyl group suggests hydrophobic characteristics, while the chloro and methyl substituents on the phenyl ring may influence its electronic properties and interactions with biological targets. The compound's molecular structure indicates potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its diverse functional groups that may interact with various biological pathways. Additionally, the presence of multiple stereocenters may lead to isomeric forms, which could exhibit different pharmacological profiles. Overall, this compound represents a significant interest for further research in drug discovery and development.

Formula: C₂₅H₃₂ClN₅O₃

Synonyms:

• Pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide, 5-butyl-N2-(3-chloro-4-methylphenyl)-N6-cyclopentyl-4,5,6,7-tetrahydro-6-methyl-4-oxo-

SMIP34

CAS: 1189710-20-0

SMIP34 is an inhibitor of PELP1, binding to this target with a dissociation constant (Kd) of 37.4 μM. It demonstrates efficacy in inhibiting the proliferation of cancer cells and tumor progression. Specifically, SMIP34 is effective in breast cancer research, showing activity against wild-type (WT), mutant (MT) estrogen receptor-positive (ER+), and treatment-resistant (TR)-ER+ breast cancers.

Formula: C₂₅H₃₂ClN₅O₃

Color and Shape: Solid

Molecular weight: 486.01

Ref: TM-T201153