CAS 1189947-02-1

Promethazine-d6 Hydrochloride Salt

Description:

Promethazine-d6 hydrochloride salt is a deuterated form of promethazine, which is an antihistamine commonly used to treat allergies, motion sickness, and nausea. The "d6" designation indicates that this compound contains six deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecule. This modification is often utilized in research and analytical applications, particularly in nuclear magnetic resonance (NMR) spectroscopy, to enhance the clarity of spectral data. Promethazine-d6 hydrochloride salt retains the pharmacological properties of its non-deuterated counterpart, including its ability to act as a sedative and antiemetic. It is typically presented as a white to off-white crystalline powder and is soluble in water and alcohol. As with other promethazine derivatives, it may exhibit side effects such as drowsiness, dry mouth, and dizziness. Proper handling and storage conditions are essential to maintain its stability and efficacy, and it should be used in accordance with safety guidelines and regulations.

Formula: C₁₇H₂₁ClN₂S

Synonyms:

• RP 3277-d6 Hydr
• Promethazine-d6 Hydrochloride Salt
• Dimapp-d6 Hydrochloride
• 10-{2-[Di(methyl-d3)amino]propyl}phenothiazine hydrochloride
• Diphergan-d6 Hydroc
• Promethazine-d6 HCl
• N,N-Di(Methyl-d3),α-Methyl-10H-phenothiazine-10-ethanaMine Hydrochloride
• (+/-)-Promethazine-d6 Hydrochloride
• N,N-Di(methyl-d3),a-methyl-10H-phenothiazine-10-ethanamine Hydrochloride
• RP 3277-d6 Hydrochloride
• [2-Di(methyl-d3)amino-2-methyl]ethyl-N-dibenzoparathiazine Hydrochloride

Promethazine-d6

CAS: 1189947-02-1

Formula: C₁₇H₁₄D₆N₂S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 290.46 36.46

Ref: 4Z-P-187

Promethazine-d6 Hydrochloride

Controlled Product

CAS: 1189947-02-1

Applications Antihistaminic, antiemetic, CNS depressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Edge, W., et al.: J. Pharm. Pharmacol., 5, 279 (1953), Huang, et al.: J. Pharm. Sci., 59, 772 (1970), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 5, 429 (1976)

Formula: C₁₇₂H₆H₁₄N₂S·ClH

Color and Shape: Neat

Molecular weight: 326.92

Ref: TR-P757002