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CAS 1189953-78-3

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Erlotinib-d6 Hydrochloride

Description:
Erlotinib-d6 Hydrochloride is a deuterated form of Erlotinib, which is an epidermal growth factor receptor (EGFR) inhibitor primarily used in the treatment of non-small cell lung cancer and pancreatic cancer. The "d6" designation indicates that the compound contains six deuterium atoms, which are stable isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful for research purposes, particularly in studies involving drug metabolism and pharmacodynamics. Erlotinib-d6 Hydrochloride retains the core structure of Erlotinib, which includes a quinazoline ring and a side chain that contributes to its biological activity. The hydrochloride salt form improves the solubility and stability of the compound in aqueous solutions. As a research chemical, it is often utilized in analytical chemistry and drug development studies to trace metabolic pathways and interactions in biological systems.
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Found 3 products.
  • Erlotinib-d6 HCl
    TLC
    + Info

    Erlotinib-d6 HCl

    CAS:
    Formula:C22H17D6N3O4·HCl
    Color and Shape:Off-White Solid
    Molecular weight:399.48 36.46

    Ref: 4Z-E-282

    5mg
    To inquire
    10mg
    1,456.00€
    25mg
    2,670.00€
    50mg
    4,368.00€
    100mg
    To inquire
  • Erlotinib-d6 hydrochloride
    Targetmol
    + Info

    Erlotinib-d6 hydrochloride

    CAS:
    Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.
    Formula:C22H24ClN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:435.93

    Ref: TM-T19312

  • Erlotinib-d6 Hydrochloride
    TRC
    + Info

    Erlotinib-d6 Hydrochloride

    Controlled Product
    CAS:
    <p>Applications Labelled Erlotinib (E625000). Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001), Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004), Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005),<br></p>
    Formula:C222H6H17N3O4·ClH
    Color and Shape:Neat
    Molecular weight:435.93

    Ref: TR-E625002

    1mg
    271.00€
    10mg
    1,837.00€