CAS 1189974-82-0

MITOXANTRONE-D8

Description:

MITOXANTRONE-D8 is a deuterated analog of mitoxantrone, a synthetic anthracenedione used primarily in cancer therapy. As a chemical substance, it retains the core structure of mitoxantrone but incorporates deuterium atoms, which are heavier isotopes of hydrogen. This modification can enhance the stability and metabolic tracking of the compound in biological studies. MITOXANTRONE-D8 exhibits similar pharmacological properties to its non-deuterated counterpart, including its mechanism of action as a topoisomerase II inhibitor, which interferes with DNA replication and transcription, ultimately leading to cell death. It is characterized by its blue color and is soluble in various organic solvents. The presence of deuterium can also influence its pharmacokinetics and pharmacodynamics, making it a valuable tool in research for understanding drug metabolism and efficacy. As with all chemotherapeutic agents, safety and handling precautions are essential due to its potential toxicity and side effects associated with cancer treatment.

Formula: C₂₂H₂₈N₄O₆

Synonyms:

• MITOXANTRONE-D8
• 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl-d4)aMino]ethyl]aMino]-9,10-anthracenedione
• (1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione-D8)
• 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione-d
• 1,4-Bis[(2-(2-hydroxyethylaMino-d4)ethyl)aMino]-5,8-dihydroxyanthraquinone

Mitoxantrone-d8 DiHCl

CAS: 1189974-82-0

Formula: C₂₂H₂₀D₈N₄O₆·2HCl

Molecular weight: 452.54 2*36.46

Ref: 4Z-M-088006

Mitoxantrone-d8

Controlled Product

CAS: 1189974-82-0

Formula: C₂₂₂H₈H₂₀N₄O₆

Color and Shape: Neat

Molecular weight: 452.53

Ref: TR-M373427