CAS 119-04-0: D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-

Description:D-Streptamine is an aminoglycoside antibiotic that plays a significant role in the treatment of various bacterial infections. It is characterized by its complex glycosidic structure, which includes multiple amino and deoxy sugar components, contributing to its biological activity. The compound features a unique arrangement of sugar moieties, specifically a β-L-idopyranosyl and a β-D-ribofuranosyl unit, linked through glycosidic bonds. D-Streptamine exhibits a high affinity for bacterial ribosomes, inhibiting protein synthesis, which is crucial for bacterial growth and replication. Its mechanism of action primarily involves binding to the 30S ribosomal subunit, leading to misreading of mRNA and ultimately resulting in the production of nonfunctional proteins. This antibiotic is particularly effective against Gram-negative bacteria and is often used in combination with other antibiotics to enhance therapeutic efficacy. However, its use is limited by potential nephrotoxicity and ototoxicity, necessitating careful monitoring during treatment. Overall, D-Streptamine remains an important compound in the field of antimicrobial therapy.

Formula:C₂₃H₄₆N₆O₁₃

InChI:InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1

InChI key:InChIKey=PGBHMTALBVVCIT-VCIWKGPPSA-N

SMILES:OCC1OC(OC2C(O)C(N)CC(N)C2OC3OC(CN)C(O)C(O)C3N)C(O)C1OC4OC(CN)C(O)C(O)C4N

Synonyms:
D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-β-<smallcap>D-ribofuranosyl-(1→5)]-2-deoxy-
D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-<smallcap>D-glucopyranosyl-(1→4)]-2-deoxy-
Actilin
Actiline
Antibiotic 10676
Antibiotique EF 185
D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-
Dekamycin III
Enterfram
Fradiomycin B
See more synonyms
Framicetina
Framidal
Framycetin
Framycetine
Framycin
Framygen
Francetin
Fraquinol
Leo Red Dry Cow
Neomycin B
O-2,6-Diamino-2,6-dideoxy-β-L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)]-2-deoxy-<smallcap>D-streptamine
Neomycin solution
D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
O-2,6-Diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine

Found 6 products.

Product data	Purity	Price range	Estimated delivery
Framycetin REF: TM-T15348CAS: 119-04-0	98%	2,517.00 €	Tue 29 Apr 25
Neomycin B REF: TR-N389983CAS: 119-04-0	- - -	251.00 €~907.00 €	Tue 06 May 25
Neomycin B Hexaacetate REF: TR-N389990CAS: 119-04-0	- - -	405.00 €~2,745.00 €	Tue 06 May 25
Neomycin B REF: 3D-FN175622CAS: 119-04-0	Min. 95%	To inquire	Tue 10 Jun 25
Framycetin sulphate REF: 3D-FF150536CAS: 119-04-0 28002-70-2 4146-30-9	Min. 95%	To inquire	Mon 23 Jun 25
Neomycin solution - 10mg/mL neomycin in 0.9% NaCl REF: 3D-FN45878CAS: 119-04-0	Min. 95%	- - -	Discontinued product