CAS 119-41-5

Efloxate

Description:

Efloxate, with the CAS number 119-41-5, is a chemical compound that belongs to the class of fluoroquinolone antibiotics. It is primarily characterized by its ability to inhibit bacterial DNA gyrase and topoisomerase IV, which are essential enzymes for bacterial DNA replication and transcription. Efloxate exhibits broad-spectrum antibacterial activity, making it effective against a variety of Gram-positive and Gram-negative bacteria. The compound is typically administered in its salt form and is known for its relatively good oral bioavailability. In terms of physical properties, efloxate is generally a crystalline solid, and its solubility can vary depending on the solvent used. It is important to note that, like other fluoroquinolones, efloxate may have potential side effects, including effects on tendons and the central nervous system. As with any antibiotic, appropriate usage is crucial to minimize the risk of developing antibiotic resistance. Overall, efloxate is significant in the field of medicinal chemistry for its therapeutic applications in treating bacterial infections.

Formula: C₁₉H₁₆O₅

InChI: InChI=1S/C19H16O5/c1-2-22-19(21)12-23-14-8-9-15-16(20)11-17(24-18(15)10-14)13-6-4-3-5-7-13/h3-11H,2,12H2,1H3

InChI key: InChIKey=ZVXBAHLOGZCFTP-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC(=C1)C3=CC=CC=C3)=CC(OCC(OCC)=O)=CC2

Synonyms:

• ((4-Oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)acetic acid ethyl ester
• Efloxatum
• UNII-CZU6V3902K
• Coril
• 7-Flavone ethyl hydroxyacetate
• Eflossato
• Ethyl 7-hydroxyflavone
• Ethyl 7-flavonoxyacetate
• BRN 0313027
• Efloxate
• CCRIS 5253
• Flacethyle
• Efloxate
• Efloxato [INN-Spanish]
• Domucor
• Efloxato
• Oxiflavil
• Flavone-7-ethyl-oxyacetate
• Ethyl [(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]acetate
• Ethyl flavon-7-yloxyacetate
• Acetic acid, [(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]-, ethyl ester
• 4-18-00-00695 (Beilstein Handbook Reference)
• 7-Flavonoxyacetic acid ethyl ester
• 7-alpha-(Acetoxyethane)-oxyflavone
• Dilatan kore
• RE 1-0185
• Eflossato [DCIT]
• REC 1-0185
• ethyl [(4-oxo-2-phenyl-4H-chromen-7-yl)oxy]acetate
• Flacethyle
• Efloxate [INN:JAN]
• Acetic acid, 2-[(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]-, ethyl ester
• Ethyl-((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy) acetate
• Angorlisin
• Corosanin
• Oxyflavil
• Acetic acid, ((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)-, ethyl ester
• Recordil

Efloxate

CAS: 119-41-5

Efloxate (Angorlisin), a vasodilator, is utilized in the treatment of chronic coronary insufficiency.

Formula: C₁₉H₁₆O₅

Purity: 99.66%

Color and Shape: Solid

Molecular weight: 324.33

Ref: TM-T0151

efloxate

CAS: 119-41-5

Formula: C₁₉H₁₆O₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 324.3273

Ref: IN-DA008SHA

Efloxate

CAS: 119-41-5

Efloxate

Purity: ≥98%

Molecular weight: 324.33g/mol

Ref: 54-BUP11059

Efloxate

CAS: 119-41-5

Purity: ≥99%

Molecular weight: 324.332

Ref: 10-F979962

Efloxate

CAS: 119-41-5

Efloxate is a collagen analog that inhibits the activity of the enzyme lysyl oxidase. This inhibition prevents the cross-linking of collagen and leads to a reduction in collagen production and tissue hardening. Efloxate has been approved by the FDA for treatment of cardiac disease, autoimmune diseases, and some cancers. The drug also has anti-inflammatory properties, which may be due to its ability to inhibit inflammatory bowel disease.
Efloxate is absorbed from the gastrointestinal tract after oral administration and has been shown to have an absorption enhancer activity in rats with colitis.

Formula: C₁₉H₁₆O₅

Purity: Min. 95%

Molecular weight: 324.3 g/mol

Ref: 3D-AAA11941