CAS 1190-53-0: Buformin hydrochloride
Description:Buformin hydrochloride is a pharmaceutical compound primarily used as an antihyperglycemic agent in the management of type 2 diabetes mellitus. It belongs to the biguanide class of medications, which also includes metformin. The substance is characterized by its ability to lower blood glucose levels by decreasing hepatic glucose production, enhancing insulin sensitivity, and promoting glucose uptake in peripheral tissues. Buformin hydrochloride is typically administered orally and is known for its relatively rapid onset of action. In terms of physical properties, it is a white to off-white crystalline powder that is soluble in water, making it suitable for formulation in various dosage forms. However, its use has declined in favor of metformin due to concerns about potential side effects, including lactic acidosis. As with any medication, it is essential to consider contraindications and potential interactions with other drugs when prescribing buformin hydrochloride. Overall, while it has therapeutic benefits, careful monitoring and patient selection are crucial for safe use.
Formula:C6H15N5·ClH
InChI:InChI=1S/C6H15N5.ClH/c1-2-3-4-10-6(9)11-5(7)8;/h2-4H2,1H3,(H6,7,8,9,10,11);1H
InChI key:InChIKey=KKLWSPPIRBIEOV-UHFFFAOYSA-N
SMILES:Cl.N=C(N)NC(=N)NCCCC
- Synonyms:
- 1-Butyl-biguanid hydrochlorid
- 1-Butyl-biguanid hydrochlorid [German]
- 1-Butylbiguanide hydrochloride
- 1-Butyldiguanide hydrochloride
- 2-Butyl-1-(Diaminomethylidene)Guanidine Hydrochloride (1:1)
- Adebit
- Andere
- Biforon
- Biguanide, 1-butyl-, hydrochloride
- Biguanide, 1-butyl-, monohydrochloride
- See more synonyms
- Bigunal
- Bufonamin
- Buformin hydrochloride
- Buformine HCl
- Bulbonin
- Butyl guanylguanidine
- Butylbiguanide hydrochloride
- DBV hydrochloride
- Diabrin
- Dibetos
- Glibutide
- Gliporal
- Glybutide
- Imidodicarbonimidic diamide, N-butyl-, hydrochloride (1:1)
- Imidodicarbonimidic diamide, N-butyl-, monohydrochloride
- Insulamin
- Krebon
- N(sup 1)-n-Butylbiguanide hydrochloride
- N-Butyl-imidodicarbonimidic diamide monohydrochloride (9CI)
- N-Butylbiguanide hydrochloride
- N<sup>1</sup>-Butyl-biguanide hydrochloride
- N<sup>1</sup>-n-Butylbiguanide hydrochloride
- Nsc 113665
- Nsc 528218
- Panformin
- Sb 103
- Silubin
- Sindiatil
- Tidemol
- W37
- Ziavetine
