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CAS 119006-77-8

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Flutrimazole

Description:
Flutrimazole is an antifungal agent belonging to the triazole class, primarily used in the treatment of various fungal infections. It exhibits broad-spectrum antifungal activity by inhibiting the enzyme lanosterol 14α-demethylase, which is crucial for ergosterol synthesis in fungal cell membranes. This disruption of ergosterol production leads to increased membrane permeability and ultimately fungal cell death. Flutrimazole is characterized by its relatively low solubility in water, which can affect its bioavailability and absorption in the body. It is typically administered topically or systemically, depending on the type and severity of the infection. The compound has a favorable safety profile, with side effects generally being mild and manageable. Additionally, Flutrimazole has shown effectiveness against various dermatophytes and yeast infections, making it a valuable option in antifungal therapy. Its chemical structure includes a triazole ring, contributing to its mechanism of action and pharmacological properties. Overall, Flutrimazole is an important agent in the management of fungal diseases, particularly in dermatological applications.
Formula:C22H16F2N2
InChI:InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H
InChI key:InChIKey=QHMWCHQXCUNUAK-UHFFFAOYSA-N
SMILES:C(C1=C(F)C=CC=C1)(C2=CC=C(F)C=C2)(N3C=CN=C3)C4=CC=CC=C4
Synonyms:
  • 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole
  • 1-[(2-Fluorophenyl)-(4-fluorophenyl)-phenylmethyl]imidazole
  • 1-[o-Fluoro-a-(p-fluorophenyl)-a-phenylbenzyl]imidazole
  • 1H-Imidazole, 1-[(2-fluorophenyl)(4-fluorophenyl)phenylmethyl]-
  • Micetal
  • Ur 4056
  • Flutrimazole
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