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CAS 1190105-63-5

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3-Acetyl-17-deacetyl Rocuronium Bromide

Description:
3-Acetyl-17-deacetyl Rocuronium Bromide is a chemical compound that belongs to the class of neuromuscular blocking agents, specifically used in anesthesia to facilitate muscle relaxation during surgical procedures. It is a derivative of Rocuronium, which is a non-depolarizing neuromuscular blocker. The compound features a quaternary ammonium structure, which contributes to its pharmacological properties. Its mechanism of action involves competitive inhibition of acetylcholine at the neuromuscular junction, leading to muscle paralysis. The presence of the acetyl group enhances its solubility and stability. As a bromide salt, it is typically administered intravenously and is characterized by a rapid onset and intermediate duration of action. The compound is subject to hydrolysis and metabolism in the body, primarily by hepatic pathways. Safety and efficacy profiles are established through clinical studies, and it is essential to monitor patients for potential side effects, including respiratory depression and allergic reactions. Proper handling and storage conditions are crucial due to its pharmacological activity.
Formula:C32H53BrN2O4
Synonyms:
  • 3-Acetyl-17-deacetyl RocuroniuM BroMide
  • RocuroniuM BroMide IMpurity 17 (EP iMpurity D)
  • Rocuronium EP Impurity D
  • Rocuronium Bromide Impurity 4（Rocuronium Bromide EP Impurity D）
  • Rocuronium Bromide Impurity 4(EP Impurity D)
  • Rocuronium bromide EP impurity D
  • Rocuronium Bromide Impurity 4（Rocuronium Bromide EP Impurity D）（ Rocuronium Bromide USP RC D）
  • 1-[3α-acetoxy-17β-hydroxy-2β-(morpholin-4-yl)-5α-androstan-16β-yl]-1-(prop-2-enyl)pyrrolidinium
  • Rocuronium impurity D
  • Rocuronium Bromide EP Impurity D Bromide
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