CAS 1190307-88-0
:Sofosbuvir
Description:
Sofosbuvir is an antiviral medication primarily used in the treatment of hepatitis C virus (HCV) infections. It is classified as a nucleotide analog polymerase inhibitor, specifically targeting the HCV NS5B polymerase, which is essential for viral replication. The chemical structure of Sofosbuvir includes a phosphoramidate prodrug that is converted in the body to its active form, which then interferes with viral RNA synthesis. Sofosbuvir is known for its high efficacy and is often used in combination with other antiviral agents to enhance treatment outcomes. It is typically administered orally and has a favorable pharmacokinetic profile, allowing for once-daily dosing. The substance is generally well-tolerated, with a side effect profile that may include fatigue, headache, and nausea. Its development marked a significant advancement in hepatitis C therapy, contributing to the potential for cure in many patients. As a prescription medication, Sofosbuvir is subject to regulatory oversight and should be used under medical supervision.
Formula:C22H29FN3O9P
InChI:InChI=1S/C22H29FN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16+,18+,20+,22+,36-/m0/s1
InChI key:InChIKey=TTZHDVOVKQGIBA-IQWMDFIBSA-N
SMILES:C[C@]1(F)[C@@H](O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OC(C)C)=O)C)=O)[C@H]1O)N3C(=O)NC(=O)C=C3
Synonyms:- (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
- <span class="text-smallcaps">L</span>-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-uridylyl]-, 1-methylethyl ester
- Gs-7977
- Hepcinat
- Hepcvir
- Isopropyl (2S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propionate
- L-Alanine, N-[[p(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-p-phenyl-5'-uridylyl]-, 1-methylethyl ester
- Psi 7977
- Resof
- Sofasbuvir
- Sofosbuvir Form6
- Sofosvuvir Form6
- Sopropyl-(2S)-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl]-4-fluoro-3-hydroxy-4-methy-ltetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate
- Sovaldi
- Sovihep
- sovaldi API
- Sofosbuvir(cGMP)
- L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-uridylyl]-, 1-methylethyl ester
- (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4 dihydropryimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2yl) methoxy)(phenoxy)phosphoryl)amino) propanoate
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Found 8 products.
Sofosbuvir
CAS:Formula:C22H29FN3O9PPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:529.45Sofosbuvir
CAS:Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatmentFormula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.45Sofosbuvir
CAS:<p>Potent inhibitor of viral RNA polymerase called non-structural protein 5B (NS5B). This nucleotide analog is effective against Hepatitis C virus (HCV) infection since it inhibits viral RNA replication. Sofosbuvir is a prodrug and gets triphosphorylated in the liver cells, generating biologically active compound with anti-viral activity.</p>Formula:C22H29FN3O9PPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:529.45 g/molSofosbuvir - Bio-X ™
CAS:<p>Sofosbuvir is an antiviral agent that is used for the treatment of hepatitis C infections and is used in combination with other antiviral agents. This drug is an inhibitor of viral RNA polymerase called non-structural protein 5B (NS5B). As a result, it inhibits viral RNA replication.</p>Formula:C22H29FN3O9PPurity:Min. 95%Color and Shape:PowderMolecular weight:529.45 g/mol
