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Sofosbuvir

CAS 1190307-88-0: Sofosbuvir

Description:Sofosbuvir is an antiviral medication primarily used in the treatment of hepatitis C virus (HCV) infections. It is classified as a nucleotide analog polymerase inhibitor, specifically targeting the HCV NS5B polymerase, which is essential for viral replication. The chemical structure of Sofosbuvir includes a phosphoramidate prodrug that is converted in the body to its active form, which then interferes with viral RNA synthesis. Sofosbuvir is known for its high efficacy and is often used in combination with other antiviral agents to enhance treatment outcomes. It is typically administered orally and has a favorable pharmacokinetic profile, allowing for once-daily dosing. The substance is generally well-tolerated, with a side effect profile that may include fatigue, headache, and nausea. Its development marked a significant advancement in hepatitis C therapy, contributing to the potential for cure in many patients. As a prescription medication, Sofosbuvir is subject to regulatory oversight and should be used under medical supervision.

Formula:C22H29FN3O9P

InChI:InChI=1S/C22H29FN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16+,18+,20+,22+,36-/m0/s1

InChI key:InChIKey=TTZHDVOVKQGIBA-IQWMDFIBSA-N

SMILES:O=C(OC(C)C)C(NP(=O)(OC=1C=CC=CC1)OCC2OC(N3C=CC(=O)NC3=O)C(F)(C)C2O)C

  • Synonyms:
  • (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • <span class="text-smallcaps">L</span>-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-uridylyl]-, 1-methylethyl ester
  • Gs-7977
  • Hepcinat
  • Hepcvir
  • Isopropyl (2S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propionate
  • L-Alanine, N-[[p(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-p-phenyl-5'-uridylyl]-, 1-methylethyl ester
  • Psi 7977
  • Resof
  • Sofasbuvir
  • See more synonyms
  • Sofosbuvir Form6
  • Sofosvuvir Form6
  • Sopropyl-(2S)-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl]-4-fluoro-3-hydroxy-4-methy-ltetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate
  • Sovaldi
  • Sovihep
  • sovaldi API
  • Sofosbuvir(cGMP)
  • L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-uridylyl]-, 1-methylethyl ester
  • (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4 dihydropryimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2yl) methoxy)(phenoxy)phosphoryl)amino) propanoate
  • Sofosbuvir
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Found 7 products.

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Sofosbuvir, 98%

CAS:1190307-88-0

Ref: AC-46193

250mg332.00 €
Estimated delivery in United States, on Friday 28 Feb 2025
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Sofosbuvir

CAS:1190307-88-0

Ref: 4Z-S-055002

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Sofosbuvir

CAS:1190307-88-0

Ref: 7W-GP2923

10mg437.00 €
25mg744.00 €
50mg1,279.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Sofosbuvir

CAS:1190307-88-0

Ref: TM-T6676

1g170.00 €
5mg49.00 €
10mg69.00 €
50mg88.00 €
100mg96.00 €
500mg143.00 €
1mL*10mM (DMSO)57.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Sofosbuvir

CAS:1190307-88-0

Ref: 3D-FS45410

1g410.00 €
2g501.00 €
5g772.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Sofosbuvir - Bio-X ™

CAS:1190307-88-0

Ref: 3D-BS165550

10mg147.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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PSI-7977-D5

Controlled Product
CAS:1190307-88-0

Ref: TR-P839643

25mg2,239.00 €
2500µg348.00 €
Estimated delivery in United States, on Monday 14 Apr 2025
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