CAS 1190379-70-4

Formula: C25H34N6O

InChI: InChI=1S/C25H34N6O/c1-31-13-10-19-14-21(9-8-20(19)16-31)29-25-28-15-22(17-6-7-17)23(30-25)26-11-3-12-27-24(32)18-4-2-5-18/h8-9,14-15,17-18H,2-7,10-13,16H2,1H3,(H,27,32)(H2,26,28,29,30)

InChI key: KKISLZKMBSCLSS-UHFFFAOYSA-N

SMILES: CN1CCC2=C(C1)C=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4CCC4)C5CC5

MRT68921

CAS: 1190379-70-4

MRT68921

Formula: C₂₅H₃₄N₆O

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 434.58

Ref: 54-BUP05833

MRT68921

CAS: 1190379-70-4

Formula: C₂₅H₃₄N₆O

Purity: 98%

Molecular weight: 434.5771

Ref: IN-DA000I41

MRT68921

CAS: 1190379-70-4

MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

Formula: C₂₅H₃₄N₆O

Purity: 99.23%

Color and Shape: Solid

Molecular weight: 434.5771

Ref: TM-T6899

MRT68921

CAS: 1190379-70-4

N-(3-((5-Cyclopropyl-2-((2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)amino)pyrimidin-4-yl)amino)propyl)cyclobutanecarboxamide

Formula: C₂₅H₃₄N₆O

Purity: 99%

Molecular weight: 434.58

Ref: IN-DG00800356

MRT 68921 dihydrochloride

CAS: 1190379-70-4

MRT 68921 dihydrochloride is a novel anthelmintic drug that inhibits the formation of autophagosomes. It has been shown to be effective against nematodes, such as parasitic nematodes and free-living nematodes, which are parasites that live in animals' intestines. The drug blocks the formation of autophagosomes by inhibiting key proteins involved in autophagy, preventing the degradation of cellular components and thus killing the parasite. MRT 68921 dihydrochloride binds to a conserved region in the cysteine protease domain of the protein Atg4B, thereby inhibiting its activity. This inhibition prevents the degradation of cellular components and leads to cell death.

Formula: C₂₅H₃₄N₆O

Purity: Min. 95%

Molecular weight: 434.58 g/mol

Ref: 3D-FM172881