CAS 1190389-15-1
:Vibegron
Description:
Vibegron is a pharmaceutical compound primarily used as a treatment for overactive bladder (OAB). It functions as a selective beta-3 adrenergic agonist, which means it stimulates beta-3 adrenergic receptors in the bladder, leading to relaxation of the detrusor muscle and increased bladder capacity. This mechanism helps alleviate symptoms associated with OAB, such as urgency and frequency of urination. Vibegron is characterized by its relatively high selectivity for the beta-3 receptor compared to other adrenergic receptors, which contributes to its therapeutic efficacy and minimizes side effects. The compound is typically administered orally and has a favorable pharmacokinetic profile, including good absorption and a manageable half-life. Its chemical structure includes specific functional groups that contribute to its activity and solubility. As with any medication, potential side effects may include headache, nausea, and hypertension, but it is generally well-tolerated. Overall, Vibegron represents a significant advancement in the pharmacological management of OAB.
Formula:C26H28N4O3
InChI:InChI=1S/C26H28N4O3/c31-24-14-15-27-23-13-12-22(30(23)24)26(33)29-19-8-6-17(7-9-19)16-20-10-11-21(28-20)25(32)18-4-2-1-3-5-18/h1-9,14-15,20-22,25,28,32H,10-13,16H2,(H,29,33)/t20-,21+,22-,25+/m0/s1
InChI key:InChIKey=DJXRIQMCROIRCZ-XOEOCAAJSA-N
SMILES:C(NC1=CC=C(C[C@H]2N[C@@]([C@H](O)C3=CC=CC=C3)(CC2)[H])C=C1)(=O)[C@H]4N5C(CC4)=NC=CC5=O
Synonyms:- MK 4618
- Gemtesa
- Vibegron
- Pyrrolo[1,2-a]pyrimidine-6-carboxamide, 4,6,7,8-tetrahydro-N-[4-[[(2S,5R)-5-[(R)-hydroxyphenylmethyl]-2-pyrrolidinyl]methyl]phenyl]-4-oxo-, (6S)-
- (6S)-4,6,7,8-Tetrahydro-N-[4-[[(2S,5R)-5-[(R)-hydroxyphenylmethyl]-2-pyrrolidinyl]methyl]phenyl]-4-oxopyrrolo[1,2-a]pyrimidine-6-carboxamide
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Vibegron
CAS:Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).Formula:C26H28N4O3Color and Shape:SolidMolecular weight:444.53
