CAS 1191237-69-0
:(2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
Description:
The chemical substance with the name "(2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile" and CAS number "1191237-69-0" is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a tetrahydrofuran ring, which is a five-membered cyclic ether, and contains multiple hydroxyl (-OH) groups that contribute to its hydrophilicity and potential reactivity. The presence of a carbonitrile (-C≡N) group indicates a potential for nucleophilic reactions, while the aminopyrrolo-triazine moiety suggests biological activity, possibly as a pharmaceutical agent. The stereochemical configuration (2R,3R,4S,5R) implies that the compound has specific spatial arrangements that can influence its interaction with biological targets. Overall, this compound may exhibit interesting properties in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. Its solubility, stability, and reactivity would be influenced by the functional groups and the overall molecular structure.
- (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
Remdesivir Impurity 34 (GS 441524)
CAS:Formula:C12H13N5O4Color and Shape:White To Off-White SolidMolecular weight:291.27(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]Triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Carbonitrile
CAS:(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]Triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-CarbonitrilePurity:98%Molecular weight:291.26g/molGS-441524
CAS:GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.Formula:C12H13N5O4Purity:98.78% - 99.75%Color and Shape:SolidMolecular weight:291.26Remdesivir Impurity 34-13C-d3-15N2 (GS-441524-13C-d3-15N2)
CAS:Formula:C1113CH10D3N315N2O4Molecular weight:297.26GS-441524 (Remdesivir Metabolite)
CAS:Formula:C12H13N5O4Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:291.26(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS:Applications (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile is a predominant metabolite of remdesivir with great potential for Covid-19 treatment.
References Yan, V. C., et al.: ACS Med. Chem., 11, 1361 (2020)Formula:C12H13N5O4Color and Shape:NeatMolecular weight:291.2627Remdesivir impurity 7
CAS:Remdesivir is an antiviral drug. It is an RNA-dependent RNA polymerase inhibitor that has been shown to be effective against a broad range of RNA viruses, including influenza A and B, rhinovirus, respiratory syncytial virus, and parainfluenza virus. Remdesivir impurity 7 (impurity) is a byproduct of the synthesis process of remdesivir. It is a white crystalline solid with a strong chemical odor. This impurity can be synthesized in high purity as well as in custom specifications to meet the needs of pharmaceutical companies developing new drugs.
Formula:C15H24NO5PPurity:Min. 95%Molecular weight:329.33 g/molGS 441524
CAS:Nucleoside analog with antiviral activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is a pro-drug and undergoes intracellular phosphorylation resulting in the active triphosphate metabolite. The triphosphorylated GS 441524 analog competes with natural nucleoside triphosphates and interferes with viral RNA synthesis. In previous studies it was tested in vitro as well as in experimental animals and showed good safety profile.Formula:C12H13N5O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:291.26 g/mol(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS:Formula:C12H13N5O4Purity:98%Molecular weight:291.267
![(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]Triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahyd…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1007977.jpg&w=3840&q=75)
![2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM3891.02-0025.jpg&w=3840&q=75)
![(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahyd…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FA606090.jpg&w=3840&q=75)
![(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahyd…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF547057.jpg&w=3840&q=75)
