CAS 119141-89-8

Omeprazole

Description:

Omeprazole is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers by reducing stomach acid production. It is characterized by its chemical formula, which includes a benzimidazole ring, a methoxy group, and a pyridine moiety, contributing to its pharmacological activity. The substance is typically administered in its racemic form and is known for its high lipophilicity, allowing for effective absorption in the gastrointestinal tract. Omeprazole is often formulated as enteric-coated tablets to protect it from degradation in the acidic environment of the stomach, ensuring its release in the more neutral pH of the intestines. Its mechanism of action involves the irreversible inhibition of the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased gastric acid secretion. Omeprazole is generally well-tolerated, though long-term use may be associated with certain risks, including nutrient malabsorption and gastrointestinal infections.

Formula: C₁₇H₁₉N₃O₃S

InChI: InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

InChI key: InChIKey=SUBDBMMJDZJVOS-XMMPIXPASA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3

Synonyms:

• (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
• (R)-Esomeprazole
• 1H-Benzimidazole, 5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (R)-
• 1H-Benzimidazole, 6-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 1H-Benzimidazole-1-acetic acid, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (+)-
• 2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine
• 5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
• 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• Losec
• Mepral
• Mopral
• Omepral
• Omerprazole
• R-(+)-Omeprazole
• Zoltum
• (S)-OMEPRAZOLE
• R-Omeparazole
• Omeprazole Impurity N
• H 168/68
• 6-methoxy-2-[(R)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
• Omeprazole R-Isomer
• Esomeprazole EP Impurity F
• 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE
• 5-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]sulfinyl]-1H-benziMidazole
• 5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE
• EsoMeprazole iMpurity F
• Erythromycine Thiocynate
• Omeprazole Impurity 33
• ANTRA
• GASTROLOC
• omeprazole impurity B (r-omeprazole)
• Omeprazole impurity 18/(R)-Omeprazole/(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
• Omeprazole impurity N (R)-Omeprazole
• (R)-6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
• GASTROGARD
• PRILOSEC
• 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE
• Esomeprazole Sodium Impurity 15

1H-Benzimidazole,5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-

CAS: 119141-89-8

Formula: C₁₇H₁₉N₃O₃S

Purity: 96%

Color and Shape: Solid

Molecular weight: 345.4161

Ref: IN-DA00HEY2

(R)-Omeprazole

CAS: 119141-89-8

Formula: C₁₇H₁₉N₃O₃S

Color and Shape: Off-White Solid

Molecular weight: 345.42

Ref: 4Z-O-024

(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

CAS: 119141-89-8

Purity: 95.0%

Molecular weight: 345.4200134277344

Ref: 10-F448256

(R)-Omeprazole

CAS: 119141-89-8

Omeprazole is a proton pump inhibitor that inhibits gastric acid secretion by binding to the H+/K+ ATPase enzyme in the secretory canaliculi of the parietal cells. Omeprazole has been shown to have a protective effect in animal models against infection with Salmonella enterica serovar Typhimurium, and also protects against ulcers caused by Helicobacter pylori infection. Omeprazole is used as an adjunct treatment for patients with non-infectious gastroesophageal reflux disease (GERD) or active duodenal ulcers. It has also been used for the prevention of stress-related mucosal damage in critically ill patients, although it is not approved for this use. Omeprazole can be administered orally or by injection. When administered orally, omeprazole may cause gastrointestinal side effects such as nausea, abdominal pain, and diarrhea. Omeprazole can interact with other drugs such

Formula: C₁₇H₁₉N₃O₃S

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 345.42 g/mol

Ref: 3D-FO165430

(R)-Omeprazole

CAS: 119141-89-8

(R)-Omeprazole is a useful organic compound for research related to life sciences. The catalog number is T66287 and the CAS number is 119141-89-8.

Formula: C₁₇H₁₉N₃O₃S

Color and Shape: Solid

Molecular weight: 345.42

Ref: TM-T66287