CAS 119169-78-7

Epristeride

Description:

Epristeride is a synthetic compound primarily known for its role as a selective inhibitor of the enzyme 5-alpha-reductase, which is involved in the conversion of testosterone to dihydrotestosterone (DHT). This inhibition is significant in the treatment of conditions such as benign prostatic hyperplasia and androgenetic alopecia. Epristeride is characterized by its chemical structure, which includes specific functional groups that contribute to its biological activity and selectivity. The compound is typically administered in oral form and has been studied for its pharmacokinetics, including absorption, distribution, metabolism, and excretion. Its efficacy and safety profile have been evaluated in clinical settings, highlighting its potential benefits in managing hormone-related disorders. Additionally, like many pharmaceuticals, epristeride may exhibit side effects, which necessitate careful monitoring during treatment. Overall, epristeride represents a targeted approach in the modulation of androgen levels, showcasing the intricate relationship between chemical structure and biological function in medicinal chemistry.

Formula: C₂₅H₃₇NO₃

InChI: InChI=1S/C25H37NO3/c1-23(2,3)26-21(27)20-9-8-18-17-7-6-16-14-15(22(28)29)10-12-24(16,4)19(17)11-13-25(18,20)5/h6,14,17-20H,7-13H2,1-5H3,(H,26,27)(H,28,29)/t17-,18-,19-,20+,24-,25-/m0/s1

InChI key: InChIKey=VAPSMQAHNAZRKC-PQWRYPMOSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C=C(C(O)=O)CC4)(CC1)[H])[H])(CC[C@@H]2C(NC(C)(C)C)=O)[H]

Synonyms:

• (17b)-17-[[(1,1-Dimethylethyl)amino]carbonyl]androsta-3,5-diene-3-carboxylic Acid
• (17beta)-17-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylic acid
• 119169-78-7
• 17-(Tert-Butylcarbamoyl)Androsta-3,5-Diene-3-Carboxylic Acid
• 17β-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylic acid
• Androsta-3,5-Diene-3-Carboxylic Acid, 17-[[(1,1-Dimethylethyl)Amino]Carbonyl]-, (17Beta)-
• Androsta-3,5-diene-3-carboxylic acid, 17-[[(1,1-dimethylethyl)amino]carbonyl]-, (17β)-
• N-tert-Butylandrosta-3,5-diene-17β-carboxamide-3-carboxylic acid
• Ono 9302
• Skf 105657
• Epristeride

Androsta-3,5-diene-3-carboxylic acid, 17-[[(1,1-dimethylethyl)amino]carbonyl]-, (17β)-

CAS: 119169-78-7

Formula: C₂₅H₃₇NO₃

Purity: 99%

Molecular weight: 399.5662

Ref: IN-DA000I9P

Epristeride

CAS: 119169-78-7

Formula: C₂₅H₃₇NO₃

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 399.57

Ref: 7W-GP0186

Epristeride

CAS: 119169-78-7

Epristeride

Purity: ≥98%

Molecular weight: 399.57g/mol

Ref: 54-BUP04047

Epristeride

CAS: 119169-78-7

Formula: C₂₅H₃₇NO₃

Color and Shape: Off-White Solid

Molecular weight: 399.58

Ref: 4Z-E-112011

Epristeride

CAS: 119169-78-7

Purity: 99%

Molecular weight: 399.575

Ref: 10-F979380

Epristeride

Controlled Product

CAS: 119169-78-7

Applications Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5α-reductase isoform 2. It is used in the treatment of benign prostatic hyperplasia.
References Levy, M., et al.: J. Steroid Biochem. Mol. Biol., 48, 197 (1994); Smith, C., et al.: J. Clin. Endocrinol. Metab., 81, 1361 (1996);

Formula: C₂₅H₃₇NO₃

Color and Shape: Neat

Molecular weight: 399.566

Ref: TR-E590055

Epristeride

CAS: 119169-78-7

Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.

Formula: C₂₅H₃₇NO₃

Purity: 98.12% - >99.99%

Color and Shape: Solid

Molecular weight: 399.57

Ref: TM-T15239