CAS 119192-09-5

1-(4-Nitrobenzyl)-1H-1,2,4-triazole

Description:

1-(4-Nitrobenzyl)-1H-1,2,4-triazole is an organic compound characterized by its triazole ring, which is a five-membered heterocyclic structure containing three nitrogen atoms. The presence of the 4-nitrobenzyl group enhances its chemical reactivity and solubility properties. This compound typically exhibits a yellow to orange color due to the nitro group, which can also influence its electronic properties. It is known for its potential applications in various fields, including pharmaceuticals and agrochemicals, often serving as an intermediate in the synthesis of more complex molecules. The compound may exhibit biological activity, making it of interest in medicinal chemistry. Its stability and reactivity can be influenced by environmental factors such as pH and temperature. Additionally, the presence of the nitro group can impart specific characteristics such as increased polarity and potential for hydrogen bonding. Safety data should be consulted for handling and storage, as nitro compounds can be sensitive and may pose health risks.

Formula: C₉H₈N₄O₂

InChI: InChI=1S/C9H8N4O2/c14-13(15)9-3-1-8(2-4-9)5-12-7-10-6-11-12/h1-4,6-7H,5H2

InChI key: InChIKey=NVRYCUYVBBCXHT-UHFFFAOYSA-N

SMILES: C(C1=CC=C(N(=O)=O)C=C1)N2C=NC=N2

Synonyms:

• 1-(4-Nitrobenzyl)-1,2,4-triazole
• 1-(4-Nitrobenzyl)-1H-1,2,4-Triazole
• 1-(4-Nitrophenyl)Methyl-1,2,4-Triazole
• 1H-1,2,4-Triazole, 1-[(4-nitrophenyl)methyl]-
• 4-(1,2,4-Triazol-1-ylmethyl)nitrobenzene
• 1-[(4-Nitrophenyl)methyl]-1H-1,2,4-triazole

1H-1,2,4-Triazole, 1-[(4-nitrophenyl)methyl]-

CAS: 119192-09-5

Formula: C₉H₈N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.1854

Ref: IN-DA000IB7

1-(4-Nitrobenzyl)-1H-1,2,4-triazole

CAS: 119192-09-5

1-(4-Nitrobenzyl)-1H-1,2,4-triazole

Purity: 98%

Molecular weight: 204.19g/mol

Ref: 54-OR1063190

1-(4-Nitrobenzyl)-1,2,4-triazole

CAS: 119192-09-5

Formula: C₉H₈N₄O₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 204.19

Ref: 3B-N1007

1-[(4-Nitrophenyl)methyl]-1H-1,2,4-triazole

CAS: 119192-09-5

Formula: C₉H₈N₄O₂

Purity: ≥98%

Molecular weight: 204.189

Ref: 10-F076492

1-(4-Nitrobenzyl)-1H-1,2,4-triazole

Controlled Product

CAS: 119192-09-5

Applications 1-(4-Nitrobenzyl)-1H-1,2,4-triazole is used in method for preparing Rizatriptan Benzoate intermediate.
References Chen, Y., et al.: Faming Zhuanli Shenqing, (2018);

Formula: C₉H₈N₄O₂

Color and Shape: Yellow

Molecular weight: 204.18

Ref: TR-N900988

1-[(4-Nitrophenyl)methyl]-1H-1,2,4-triazole

CAS: 119192-09-5

1-[(4-Nitrophenyl)methyl]-1H-1,2,4-triazole (NPT) is a drug that is used to treat migraine. It is an effective and fast acting drug that has been shown to be more efficient than other triptans. NPT inhibits the uptake of serotonin by binding to its receptors in the brain and causing vasoconstriction. The compound has been found to be safe for use in humans. However, it may cause impurities such as genotoxic nitro groups which are harmful to cells if present at high concentrations. There are various techniques that can be used to measure the kinetics of NPT and determine whether it has been hydrogenated during synthesis or not. These include calibration curves, HPLC, and GC methods.

Formula: C₉H₈N₄O₂

Purity: Min. 95%

Molecular weight: 204.19 g/mol

Ref: 3D-FN149526