CAS 1191951-57-1

4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide

Description:

4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide is a chemical compound characterized by its unique structure, which includes a dodecyl chain, a thiadiazole ring, and a benzenesulfonamide moiety. This compound typically exhibits properties associated with surfactants due to the presence of a long hydrophobic dodecyl chain, which enhances its solubility in organic solvents and its ability to interact with various surfaces. The thiadiazole ring contributes to its potential biological activity, as such heterocycles are often involved in pharmacological applications. The sulfonamide group can impart additional solubility in polar solvents and may also influence the compound's reactivity and interaction with biological systems. Overall, this compound may exhibit amphiphilic characteristics, making it useful in applications such as drug delivery, emulsification, or as a surfactant in various chemical processes. Its specific applications and behavior would depend on the context of use, including concentration, environment, and the presence of other chemical species.

Formula: C₂₀H₃₁N₃O₂S₂

InChI: InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)

InChI key: InChIKey=BYWWNRBKPCPJMG-UHFFFAOYSA-N

SMILES: S(NC1=NN=CS1)(=O)(=O)C2=CC=C(CCCCCCCCCCCC)C=C2

Synonyms:

• 4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
• Benzenesulfonamide, 4-dodecyl-N-1,3,4-thiadiazol-2-yl-
• PHT 427

Benzenesulfonamide, 4-dodecyl-N-1,3,4-thiadiazol-2-yl-

CAS: 1191951-57-1

Formula: C₂₀H₃₁N₃O₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 409.6090

Ref: IN-DA000IAU

4-Dodecyl-N-(1,3,4-Thiadiazol-2-Yl)Benzenesulfonamide

CAS: 1191951-57-1

4-Dodecyl-N-(1,3,4-Thiadiazol-2-Yl)Benzenesulfonamide

Purity: 98%

Molecular weight: 409.61g/mol

Ref: 54-OR1026273

PHT-427

CAS: 1191951-57-1

PHT-427

Purity: ≥95%

Molecular weight: 409.61g/mol

Ref: 54-BUP11174

PHT-427

CAS: 1191951-57-1

PHT-427 (CS-0223) is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).

Formula: C₂₀H₃₁N₃O₂S₂

Purity: 97.54% - >99.99%

Color and Shape: Solid

Molecular weight: 409.61

Ref: TM-T2420

PHT-427

CAS: 1191951-57-1

Purity: 98%

Molecular weight: 409.6099854

Ref: 10-F861574

PHT-427

Controlled Product

CAS: 1191951-57-1

Applications PHT-427 is a pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1). It can also be used for therapeutic use and biological study of mathematical modeling and parametric analysis of nanoparticle encapsulation and controlled release of a hydrophobic kinase inhibitor PHT-427.
References Lucero-Acuna, A., et al.: Int J Pharm, 494, 249 (2015)

Formula: C₂₀H₃₁N₃O₂S₂

Color and Shape: Neat

Molecular weight: 409.61

Ref: TR-P399158

PHT-427-d4 (Major)

Controlled Product

CAS: 1191951-57-1

Formula: C₂₀H₂₇D₄N₃O₂S₂

Color and Shape: Neat

Molecular weight: 413.63

Ref: TR-P399157

Akt Inhibitor XIV

CAS: 1191951-57-1

Akt Inhibitor XIV is a growth factor that regulates cell maturation and protein synthesis. Akt inhibitor XIV has been shown to inhibit the activity of CDK4/6, which are enzymes involved in the control of cell cycle progression. This compound has minimal toxicity, can be taken orally, and has been shown to inhibit tumor growth in xenografts. It is an analog of rapamycin and may also have similar anti-cancer effects as rapamycin.

Formula: C₂₀H₃₁N₃O₂S₂

Purity: Min. 95%

Molecular weight: 409.61 g/mol

Ref: 3D-RXB95157