CAS 119238-52-7

1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline

Description:

1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline, with the CAS number 119238-52-7, is an amino acid derivative characterized by its unique structure that includes a proline backbone and a mercapto group. This compound features a sulfur-containing thiol group, which contributes to its reactivity and potential biological activity. The presence of the methyl and oxo groups in its side chain suggests that it may participate in various biochemical processes, possibly influencing protein structure or function. As a proline derivative, it may exhibit properties such as conformational rigidity and the ability to form hydrogen bonds, which are essential in peptide synthesis and protein interactions. Its stereochemistry, indicated by the (2S) configuration, is crucial for its biological activity, as stereoisomers can have significantly different effects in biological systems. Overall, this compound may have applications in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways.

Formula: C₉H₁₅NO₃S

InChI: InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7-/m1/s1

InChI key: InChIKey=FAKRSMQSSFJEIM-RNFRBKRXSA-N

SMILES: C([C@@H](CS)C)(=O)N1[C@@H](C(O)=O)CCC1

Synonyms:

• D-Captopril
• 1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline
• D-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-
• SQ 34459
• D-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-

D-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-

CAS: 119238-52-7

Formula: C₉H₁₅NO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 217.2853

Ref: IN-DA000IFE

(R)-1-((S)-3-Mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid

CAS: 119238-52-7

(R)-1-((S)-3-Mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid

Purity: 98%

Molecular weight: 217.29g/mol

Ref: 54-OR1062974

D-Captopril

CAS: 119238-52-7

Formula: C₉H₁₅NO₃S

Color and Shape: White To Off-White Solid

Molecular weight: 217.28

Ref: 4Z-C-1731

D-Captopril

Controlled Product

CAS: 119238-52-7

Applications D-Captopril and Captopril analogues are New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors which are used clinically as antidotes for metal poisoning and bacterial infection.
References Ningning; X., et al.: Bioorg. Med. Chem. Lett., 24, 386 (2014); Guo, Y., et al.: Protein Cell, 2, 384 (2011)

Formula: C₉H₁₅NO₃S

Color and Shape: Neat

Molecular weight: 217.285

Ref: TR-C176155

D-Captopril

CAS: 119238-52-7

D-Captopril is an analog of the drug captopril, which is used to treat hypertension and heart failure. This compound has been shown to have anticancer properties by inhibiting kinases that are involved in cancer cell growth and survival. D-Captopril has been found to induce apoptosis in human and Chinese hamster ovary cells. It also enhances the anticancer effects of chloroquine and artesunate, two drugs that are commonly used for cancer treatment. Additionally, D-Captopril has been shown to inhibit tumor growth in mice models. This compound is excreted via urine and may be a promising candidate for cancer therapy as a kinase inhibitor.

Formula: C₉H₁₅NO₃S

Purity: Min. 95%

Molecular weight: 217.29 g/mol

Ref: 3D-UEA23852

D-Captopril

CAS: 119238-52-7

Formula: C₉H₁₅NO₃S

Molecular weight: 217.28

Ref: ST-EA-CP-C53020