CAS 119302-20-4

(2b,3a,5a,16b,17b)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol

Description:

The chemical substance known as (2b,3a,5a,16b,17b)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol, with the CAS number 119302-20-4, is a synthetic steroid derivative. It features a complex steroid backbone, which is characteristic of androstane compounds, and is modified with morpholine and pyrrolidine functional groups. These modifications may influence its pharmacological properties, potentially enhancing its interaction with biological targets such as hormone receptors. The presence of hydroxyl groups at the 3 and 17 positions suggests that it may exhibit biological activity related to steroid hormones. The morpholine and pyrrolidine rings could contribute to its solubility and bioavailability, making it of interest in medicinal chemistry. This compound may be studied for its potential therapeutic applications, particularly in areas related to hormonal regulation or as a scaffold for drug development. However, detailed studies on its pharmacodynamics, pharmacokinetics, and safety profile would be necessary to fully understand its characteristics and potential uses.

Formula: C₂₇H₄₆N₂O₃

InChI: InChI=1/C27H46N2O3/c1-26-8-7-20-19(21(26)16-22(25(26)31)28-9-3-4-10-28)6-5-18-15-24(30)23(17-27(18,20)2)29-11-13-32-14-12-29/h18-25,30-31H,3-17H2,1-2H3/t18-,19+,20-,21-,22-,23-,24-,25-,26-,27-/m0/s1

InChI key: InChIKey=YKHDYPFPUAWBIW-QJRNWJQSSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(C[C@H](O)[C@H](C4)N5CCOCC5)[H])(CC1)[H])[H])(C[C@@H]([C@@H]2O)N6CCCC6)[H]

Synonyms:

• (2B,3A,5A,16B,17B)-2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)Androstane-3,17-Diol(9Ci)
• (2ß ,3A,5A,16ß )-2-(4-Morpholiny)-16-(1-Pyrrolidinyl)Androstane-3,17-Diol
• (2Β,3Α,5Α,16Β,17Β)-2-Morpholin-4-Yl-16-Pyrrolidin-1-Ylandrostane-3,17-Diol
• (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3,17-diol
• 2,3-Epoxy-1H-Cyclopenta[A]Phenanthrene,Anddrostan-17-Ol Deriv
• 2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)-5-Androstane-3,17-Diol
• 2-(4-Morpholinyl)-16-(pyrrolidin-1-yl)androstane-3,17-diol
• 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol
• 3,17-Dihydroxy-2-(4-Morpholinyl)-16-(1-Pyrroliny)-Androstane
• 3,17-Dihydroxy-2-(4-Morpholinyl)-16-(1-Pyrrolinyl)-Androstane
• Androstane-3,17-Diol, 2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)
• Androstane-3,17-diol, 2-(4-morpholinyl)-16-(1-pyrrolidinyl)-, (2β,3α,5α,16β,17β)-
• Intermediates For Rocuronium Bromide-7
• (2Β,3Α,5Α,16Β,17Β)-2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)Androstane-3,17-Diol
• (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol
• （2β，3ɑ，5ɑ，16ɑ，17β）-2-（4-morpholinyl）-16-（1-pyrrolidinyl）-androstane-3，17-diol

Desallyl Deacetyl Rocuronium (2β-(Morpholin-4-yl)-16β-(pyrrolidin-1-yl)-5α-androstane-3α,17β-diol)

CAS: 119302-20-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₇H₄₆N₂O₃

Color and Shape: Off-White Powder

Molecular weight: 446.35084

Ref: 45-1A08290

Androstane-3,17-diol, 2-(4-morpholinyl)-16-(1-pyrrolidinyl)-, (2β,3α,5α,16β,17β)-

CAS: 119302-20-4

Formula: C₂₇H₄₆N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 446.6657

Ref: IN-DA000P6V

Rocuronium Bromide EP Impurity G

CAS: 119302-20-4

Formula: C₂₇H₄₆N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 446.68

Ref: 4Z-R-329

(2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol

Controlled Product

CAS: 119302-20-4

Applications This compound is used in the synthesis of the neuromuscular blocking agent rocuronium bromide.
References Srinivasan, N. et al.: Orient. J. Chem., 24, 989 (2008);

Formula: C₂₇H₄₆N₂O₃

Color and Shape: Neat

Molecular weight: 446.67

Ref: TR-M725145

Rocuronium EP Impurity G

CAS: 119302-20-4

Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.

Formula: C₂₇H₄₆N₂O₃

Purity: Min. 95%

Molecular weight: 446.67 g/mol

Ref: 3D-IR178406

Rocuronium EP Impurity G

CAS: 119302-20-4

Formula: C₂₇H₄₆N₂O₃

Molecular weight: 446.7

Ref: ST-EA-CP-R78010