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CAS 119302-91-9

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Rocuronium bromide

Description:
Rocuronium bromide is a non-depolarizing neuromuscular blocking agent commonly used in anesthesia to facilitate tracheal intubation and provide muscle relaxation during surgical procedures. It acts by competitively inhibiting the action of acetylcholine at the neuromuscular junction, leading to muscle paralysis. Rocuronium is characterized by its rapid onset of action and intermediate duration of effect, making it a preferred choice in various clinical settings. The substance is typically administered intravenously and is known for its relatively predictable pharmacokinetics. Rocuronium bromide is soluble in water and has a molecular weight that classifies it as a quaternary ammonium compound. Its safety profile includes potential side effects such as hypotension and allergic reactions, although these are relatively rare. Due to its specific characteristics, it is essential for healthcare professionals to monitor patients closely during its use to manage any adverse effects effectively. Overall, Rocuronium bromide plays a crucial role in modern anesthetic practice, providing effective muscle relaxation with a favorable onset and duration.
Formula:C32H53N2O4·Br
InChI:InChI=1S/C32H53N2O4.BrH/c1-5-14-34(15-6-7-16-34)28-20-26-24-9-8-23-19-29(36)27(33-12-17-37-18-13-33)21-32(23,4)25(24)10-11-31(26,3)30(28)38-22(2)35;/h5,23-30,36H,1,6-21H2,2-4H3;1H/q+1;/p-1/t23-,24+,25-,26-,27-,28-,29-,30-,31-,32-;/m0./s1
InChI key:InChIKey=OYTJKRAYGYRUJK-FMCCZJBLSA-M
SMILES:C(C=C)[N+]1(CCCC1)[C@@H]2[C@H](OC(C)=O)[C@]3(C)[C@@](C2)([C@]4([C@](CC3)([C@]5(C)[C@@](CC4)(C[C@H](O)[C@H](C5)N6CCOCC6)[H])[H])[H])[H].[Br-]
Synonyms:
  • (2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(morpholin-4-yl)-16-[1-(prop-2-en-1-yl)pyrrolidinium-1-yl]androstane bromide
  • Org 9426
  • [3-Hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enyl-2,3,4,5-tetrahydropyrrol-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate bromide
  • rocuronium bromid
  • Androstane, pyrrolidinium deriv.
  • Rocuronium bromide
  • (2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(morpholin-4-yl)-16-[1-(prop-2-en-1-yl)pyrrolidinium-1-yl]androstane
  • Pyrrolidinium, 1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-, bromide
  • Zemuron
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Found 12 products.