CAS 1193111-39-5

Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester

CAS: 1193111-39-5

Formula: C₁₃H₁₄N₂O₇S₃

Purity: 92%

Color and Shape: Solid

Molecular weight: 406.4545

Ref: IN-DA000IKE

1-(2,5-dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid

CAS: 1193111-39-5

1-(2,5-dioxopyrrolidin-1-yloxy)-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid

Purity: ≥95%

Ref: 54-OR471225

sulfo-SPDB

CAS: 1193111-39-5

sulfo-SPDB is a cleavable linker vital in ADC synthesis.

Formula: C₁₃H₁₄N₂O₇S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 406.45

Ref: TM-T18732

sulfo-SPDB

CAS: 1193111-39-5

Purity: 92%

Molecular weight: 406.44

Ref: 10-F986756

sulfo-SPDB

CAS: 1193111-39-5

Sulfo-SPDB is a lysine analog that has potent antitumor activity and is being evaluated as a potential cancer therapeutic agent. It inhibits tumor growth in vitro by inhibiting the expression of proteins important for cell division and survival. Sulfo-SPDB binds to the lysine residues on the surface of cells, including erythrocytes, lymphocytes, and tumor cells. This binding prevents protein synthesis and cell division. In vivo studies have shown that sulfo-SPDB is effective against human liver cancer xenografts in mice, cervical cancer xenografts in mice, and t-cell lymphoma xenografts in mice. Clinical studies are underway to determine if it is safe for use in humans.

Formula: C₁₃H₁₄N₂O₇S₃

Purity: Min. 95%

Molecular weight: 406.5 g/mol

Ref: 3D-TXB11139