CAS 1193251-61-4

5-Alkynyl-L-fucose

CAS: 1193251-61-4

Inhibits GDP-4-keto-6-deoxymannose 3,5-epimerase-4-reductase (FX), which is required for the synthesis of GDP-Fuc. 5-alkynylfucose is also incorporated into the core glycan structures of the antibody. Thus, reduced concentration of endogenous substrates of fucosyltransferase 8 (FUT8) leads to reduced fucosylation of antibodies and increased therapeutic efficacy.

Formula: C₇H₁₀O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 174.15 g/mol

Ref: 3D-MA45977

6-Alkynyl-fucose

CAS: 1193251-61-4

6-Alkynyl-fucose, a widely used fucosylation probe, acts by strongly inhibiting fucosylation and GDP-fucose synthetase FX and halting hepatoma invasion.

Formula: C₇H₁₀O₅

Color and Shape: Solid

Molecular weight: 174.15

Ref: TM-T26394