CAS 1194-21-4

2-Amino-6-chloro-4(1H)-pyrimidinone

Description:

2-Amino-6-chloro-4(1H)-pyrimidinone, with the CAS number 1194-21-4, is a heterocyclic organic compound characterized by its pyrimidine ring structure, which contains both amino and chloro substituents. This compound typically exhibits a white to off-white crystalline appearance and is soluble in polar solvents such as water and alcohols, reflecting its polar functional groups. The presence of the amino group contributes to its basicity, while the chloro substituent can influence its reactivity and potential for forming hydrogen bonds. 2-Amino-6-chloro-4(1H)-pyrimidinone is of interest in medicinal chemistry and may serve as a building block for the synthesis of various pharmaceuticals, particularly in the development of antiviral and anticancer agents. Its chemical properties, including melting point and boiling point, can vary based on purity and environmental conditions. As with many nitrogen-containing heterocycles, it may participate in various chemical reactions, including nucleophilic substitutions and condensation reactions, making it a versatile compound in organic synthesis.

Formula: C₄H₄ClN₃O

InChI: InChI=1S/C4H4ClN3O/c5-2-1-3(9)8-4(6)7-2/h1H,(H3,6,7,8,9)

InChI key: InChIKey=VBWACOJLJYUFKJ-UHFFFAOYSA-N

SMILES: ClC1=CC(=O)N=C(N)N1

Synonyms:

• 2-Amino-4-chloro-6-hydroxypyrimidine
• 2-Amino-4-chloropyrimidine-6-one
• 2-Amino-4-hydroxy-6-chloropyrimidine
• 2-Amino-6-Chloropyrimidin-4-Ol Hydrate
• 2-Amino-6-chloro-1H-pyrimidin-4-one
• 2-Amino-6-chloro-3,4-dihydropyrimidin-4-one
• 2-Amino-6-chloro-3H-pyrimidin-4-one
• 2-Amino-6-chloro-4(1H)-pyrimidinone
• 2-Amino-6-chloro-4(3H)-pyrimidinone
• 2-Amino-6-chloro-4-pyrimidinol hydrate
• 2-Amino-6-chloro-4-pyrimidinol monohydrate
• 2-Amino-6-chloro-4-pyrimidinone
• 2-amino-6-chloropyrimidin-4(3H)-one
• 4(1H)-Pyrimidinone, 2-amino-6-chloro-
• 4(3H)-Pyrimidinone, 2-amino-6-chloro-
• 4-Pyrimidinol, 2-amino-6-chloro-
• 6-Chloroisocytosine
• NSC 35655

2-Amino-4-chloro-6-hydroxypyrimidine

CAS: 1194-21-4

Formula: C₄H₄ClN₃O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 145.55

Ref: 3B-A1109

4(1H)-Pyrimidinone, 2-amino-6-chloro-

CAS: 1194-21-4

Formula: C₄H₄ClN₃O

Purity: 96%

Color and Shape: Solid

Molecular weight: 145.5471

Ref: IN-DA000IOU

2-Amino-6-chloro-pyrimidin-4-ol

CAS: 1194-21-4

2-Amino-6-chloro-pyrimidin-4-ol

Formula: C₄H₄ClN₃O

Purity: 97%

Color and Shape: pale yellow solid

Molecular weight: 145.55g/mol

Ref: 54-OR49059

2-Amino-6-chloropyrimidin-4(3H)-one

CAS: 1194-21-4

Formula: C₄H₄ClN₃O

Purity: 96%

Color and Shape: Yellow powder

Molecular weight: 145.55

Ref: 10-F078117

2-​Amino-​6-​chloro-​4-​pyrimidinol

Controlled Product

CAS: 1194-21-4

Formula: C₄H₄ClN₃O

Color and Shape: Neat

Molecular weight: 145.55

Ref: TR-A603195

2-Amino-6-chloropyrimidin-4(3h)-one

CAS: 1194-21-4

2-Amino-6-chloropyrimidin-4(3H)-one (ACPP) is a betaine that has been shown to exhibit potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). It is a mesomeric molecule, which means that it can exist as two different tautomers. The frequency of the absorption bands in the FTIR spectra for ACPP are characteristic of the carbenes and ethanolamine tautomers. The presence of these tautomers may be due to stabilization from the nucleophilic character of the nitrogen atom in betaines. Betaines are also able to form polymersized chains by reacting with themselves or other molecules, such as ethanolamine.

Formula: C₄H₄ClN₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 145.55 g/mol

Ref: 3D-FA35262