CAS 1194044-20-6: LY-2811376

Description: LY-2811376, with the CAS number 1194044-20-6, is a chemical compound that has garnered attention in pharmaceutical research, particularly in the context of its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain biological pathways, which may contribute to its efficacy in treating specific diseases. The compound exhibits a unique molecular structure that influences its solubility, stability, and interaction with biological targets. In preclinical studies, LY-2811376 has shown promise in modulating cellular processes, potentially leading to beneficial effects in conditions such as cancer or inflammatory diseases. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are critical for determining its suitability for further development. As with many investigational compounds, ongoing research is essential to fully elucidate its mechanism of action, therapeutic window, and safety profile before it can be considered for clinical use.

Formula: C₁₅H₁₄F₂N₄S

InChI: InChI=1S/C15H14F2N4S/c1-15(2-3-22-14(18)21-15)11-4-10(12(16)5-13(11)17)9-6-19-8-20-7-9/h4-8H,2-3H2,1H3,(H2,18,21)/t15-/m0/s1

Synonyms:

• (4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine
• LY 2811376

4H-1,3-Thiazin-2-amine, 4-[2,4-difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-, (4S)-

CAS: 1194044-20-6

• Formula: C₁₅H₁₄F₂N₄S
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 320.3603

(S)-4-(2,4-Difluoro-5-(Pyrimidin-5-Yl)Phenyl)-4-Methyl-5,6-Dihydro-4H-1,3-Thiazin-2-Amine

CAS: 1194044-20-6

• Molecular weight: 320.36g/mol

LY2811376

CAS: 1194044-20-6

• Purity: 99%
• Molecular weight: 320.36g/mol

LY2811376

CAS: 1194044-20-6

LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: …

• Formula: C₁₅H₁₄F₂N₄S
• Purity: 99% - 99.01%
• Color and Shape: Solid
• Molecular weight: 320.36

(S)-4-(2,4-Difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine

CAS: 1194044-20-6

• Purity: 95.0%
• Molecular weight: 320.3599853515625

LY 2811376

CAS: 1194044-20-6

Inhibitor of APP cleavage enzyme BACE1

• Formula: C₁₅H₁₄F₂N₄S
• Purity: Min. 95%
• Molecular weight: 320.36 g/mol