CAS 119413-55-7

Elgodipine

Description:

Elgodipine is a pharmaceutical compound primarily classified as a calcium channel blocker, specifically targeting L-type calcium channels. It is utilized in the management of hypertension and certain cardiovascular conditions. The substance exhibits a unique mechanism of action that not only helps in vasodilation but also has potential neuroprotective effects. Elgodipine is characterized by its ability to selectively inhibit calcium influx in vascular smooth muscle and cardiac tissues, leading to reduced vascular resistance and improved blood flow. Its pharmacokinetic profile includes moderate absorption and a relatively long half-life, allowing for once-daily dosing in clinical settings. Additionally, Elgodipine has been studied for its potential benefits in treating conditions beyond hypertension, including certain types of angina and heart failure. As with any medication, the safety profile includes potential side effects, which may vary among individuals. Overall, Elgodipine represents a significant advancement in the treatment of cardiovascular diseases, with ongoing research exploring its broader therapeutic applications.

Formula: C₂₉H₃₃FN₂O₆

InChI: InChI=1/C29H33FN2O6/c1-17(2)38-29(34)25-19(4)31-18(3)24(26(25)22-7-6-8-23-27(22)37-16-36-23)28(33)35-14-13-32(5)15-20-9-11-21(30)12-10-20/h6-12,17,26,31H,13-16H2,1-5H3

SMILES: CC(C)OC(=O)C1=C(C)NC(=C(C1c1cccc2c1OCO2)C(=O)OCCN(C)Cc1ccc(cc1)F)C

Synonyms:

• Elgodipine [INN]
• 2-((p-Fluorobenzyl)methylamino)ethyl isopropyl (+-)-1,4-dihydro-2,6-dimethyl-4-(2,3-(methylenedioxy)phenyl)-3,5-pyridinedicarboxylate
• Elgodipino
• Elgodipino [INN-Spanish]
• Elgodipinum
• Elgodipinum [INN-Latin]
• Unii-3Ji11Z5Ref
• 3,5-Pyridinedicarboxylic acid, 4-(1,3-benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-, 2-(((4-fluorophenyl)methyl)methylamino)ethyl 1-methylethyl ester, (+-)-
• 2-[(4-Fluorobenzyl)(Methyl)Amino]Ethyl Propan-2-Yl 4-(1,3-Benzodioxol-4-Yl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate

Elgodipine

CAS: 119413-55-7

Elgodipine

Purity: ≥98%

Molecular weight: 524.58g/mol

Ref: 54-BUP08039

Elgodipine

CAS: 119413-55-7

Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.

Formula: C₂₉H₃₃FN₂O₆

Purity: 99.84% - 99.98%

Color and Shape: Solid

Molecular weight: 524.58

Ref: TM-T68060