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CAS 119431-25-3

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Eliprodil

Description:
Eliprodil is a chemical compound primarily recognized for its role as a neuroprotective agent and its potential therapeutic applications in treating various neurological disorders. It is classified as a selective NMDA receptor antagonist, which means it modulates the activity of the N-methyl-D-aspartate (NMDA) receptor, a critical component in synaptic plasticity and memory function. Eliprodil has been studied for its effects on conditions such as ischemic brain injury and neurodegenerative diseases. The compound exhibits a unique pharmacological profile, influencing neurotransmitter systems, particularly glutamate, which is vital for neuronal communication. Its chemical structure includes a phenyl group and a piperidine moiety, contributing to its biological activity. Eliprodil's safety and efficacy have been evaluated in various preclinical and clinical studies, although it has not gained widespread approval for clinical use in many regions. Overall, Eliprodil represents a significant area of research in neuropharmacology, with ongoing investigations into its mechanisms and potential applications in medicine.
Formula:C20H23ClFNO
InChI:InChI=1/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2
InChI key:InChIKey=GGUSQTSTQSHJAH-UHFFFAOYSA-N
SMILES:C(CN1CCC(CC2=CC=C(F)C=C2)CC1)(O)C3=CC=C(Cl)C=C3
Synonyms:
  • (+-)-alpha-(p-Chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol
  • 1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol
  • 1-(4-Chlorophenyl)-2-[4-(4-Fluorobenzyl)Piperidin-1-Yl]Ethanol
  • 1-(4-Chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethan-1-ol
  • 1-(4-Chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanol
  • 1-Piperidineethanol, alpha-(4-chlorophenyl)-4-((4-fluorophenyl)methyl)-, (+-)-
  • 1-Piperidineethanol, alpha-(4-chlorophenyl)-4-(4-fluorophenyl)-, (+-)-
  • 1-Piperidineethanol, α-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-
  • Eliprodil [INN]
  • Sl 82-0715
  • See more synonyms
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