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CAS 119462-97-4

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2-Cyanoethyl 3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl N,N-bis(1-methylethyl)phosphoramidite

Description:
2-Cyanoethyl 3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl N,N-bis(1-methylethyl)phosphoramidite is a phosphoramidite compound commonly used in the field of organic synthesis, particularly in the synthesis of oligonucleotides. This compound features a phosphoramidite functional group, which is characterized by the presence of a phosphorus atom bonded to an amine and two alkyl groups, contributing to its reactivity in nucleophilic substitution reactions. The presence of the cyanoethyl group enhances its stability and solubility in organic solvents, while the methoxyphenyl and diphenylmethyl substituents provide steric hindrance and electronic effects that can influence its reactivity. The compound is typically handled under anhydrous conditions due to its sensitivity to moisture, which can lead to hydrolysis. Its applications extend to the development of nucleic acid-based therapeutics and diagnostics, making it a valuable reagent in molecular biology and biochemistry. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.
Formula:C32H42N3O3P
Synonyms:
  • 2-cyanoethyl (3-(((4-methoxyphenyl)diphenylmethyl)amino)propyl) diisopropylphosphoramidite
  • 2-Cyanoethyl 3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl N,N-bis(1-methylethyl)phosphoramidite
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