CAS 119478-56-7: Meropenem trihydrate

Description: Meropenem trihydrate is a broad-spectrum antibiotic belonging to the carbapenem class, primarily used to treat severe bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a wide range of Gram-positive and Gram-negative bacteria, including those resistant to other antibiotics. The trihydrate form indicates that the compound contains three molecules of water per molecule of meropenem, which can influence its solubility and stability. Meropenem is typically administered via intravenous injection due to its poor oral bioavailability. It is known for its favorable pharmacokinetic properties, including a relatively long half-life and good tissue penetration. Common side effects may include gastrointestinal disturbances, headache, and potential allergic reactions. As with other antibiotics, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed regimens. Overall, meropenem trihydrate is a critical option in the treatment of serious infections, particularly in hospital settings.

Formula: C₁₇H₂₅N₃O₅S·3H₂O

InChI: InChI=1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1

InChI key: InChIKey=CTUAQTBUVLKNDJ-OBZXMJSBSA-N

SMILES: O=C(O)C1=C(SC2CNC(C(=O)N(C)C)C2)C(C)C3N1C(=O)C3C(O)C.O

Synonyms:

• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(2S,5S)-5-(dimethylcarbamoyl)pyrrolidin-2-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4S,5R,6R)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate (1:3), (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, trihydrate, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• Meropenem (with carbonate)
• Meropenem trihydrate

Meropenem Trihydrate

CAS: 119478-56-796036-03-2

• Formula: C₁₇H₂₅N₃O₅S·3H₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 437.51

Meropenem trihydrate, 98-101%

CAS: 119478-56-7

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria. …

• Formula: C₁₇H₃₁N₃O₈S
• Purity: 98-101%
• Color and Shape: Powder or crystals or crystalline powder, White to pale yellow
• Molecular weight: 437.51

Meropenem trihydrate CRS

CAS: 119478-56-7

• Formula: C₁₇H₂₅N₃O₅S
• Molecular weight: 383.4625

Meropenem

CAS: 119478-56-7

Antibiotics nesoi

• Formula: C₁₇H₂₅N₃O₅S· 3H₂O
• Color and Shape: White Light Yellow Powder
• Molecular weight: 437.51

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.

• Formula: C₁₇H₃₁N₃O₈S
• Purity: 99.63%
• Color and Shape: Solid
• Molecular weight: 437.51

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate (1:3), (4R,5S,6S)-

CAS: 119478-56-7

• Formula: C₁₇H₃₁N₃O₈S
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 437.5083

Meropenem trihydrate

CAS: 119478-56-7

• Formula: C₁₇H₂₅N₃O₅S·3H₂O
• Purity: ≥ 98.0% (anhydrous basis)
• Color and Shape: White, off-white or faint beige crystalline powder
• Molecular weight: 437.51

Meropenem trihydrate

CAS: 119478-56-7

• Purity: ≥98%
• Molecular weight: 437.51g/mol

Meropenem trihydrate, USP grade

CAS: 119478-56-7

• Formula: C₁₇H₂₅N₃O₅S·3H₂O
• Purity: ≤ 0.1% (anhydrous basis)
• Color and Shape: White, off-white or faint beige crystalline powder
• Molecular weight: 437.51

Meropenem Trihydrate

CAS: 119478-56-7

• Formula: C₁₇H₂₅N₃O₅SH₂O
• Color and Shape: Neat
• Molecular weight: 437.51

Meropenem trihydrate

CAS: 119478-56-7

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₇H₃₁N₃O₈S
• Color and Shape: White to light yellow to light beige, Powder or crystals
• Molecular weight: 437.51

Meropenem trihydrate

CAS: 119478-56-7

• Formula: C₁₇H₂₅N₃O₅SH₂O
• Color and Shape: Neat
• Molecular weight: 437.51

Meropenem RS

CAS: 119478-56-7

• Color and Shape: White To Light Yellow Solid Crystalline Powder

Meropenem trihydrate

CAS: 119478-56-7

• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 437.510009765625

Meropenem Trihydrate

CAS: 119478-56-7

Applications Meropenem Trihydrate is a carbapenem antibiotic with wide spectrum of antibacterial. References Hickey, M.B., …

• Formula: C₁₇H₂₅N₃O₅SH₂O
• Color and Shape: Light Yellow
• Molecular weight: 437.51

Meropenem trihydrate, Antibiotic for Culture Media Use Only

CAS: 119478-56-7

Meropenem trihydrate has broad spectrum activity against Gram-positive and Gram-negative bacteria, as well as, some …

• Formula: C₁₇H₃₁N₃O₈S
• Purity: Min. 98.0 Area-%
• Molecular weight: 437.51 g/mol

Meropenem trihydrate

CAS: 119478-56-7

Inhibitor of cell-wall synthesis; carbapenem class

• Formula: C₁₇H₂₅N₃O₅S·3H₂O
• Purity: Min. 95 Area-%
• Color and Shape: Powder
• Molecular weight: 437.51 g/mol