CAS 119514-66-8
:Lifarizine
Description:
Lifarizine is a chemical compound primarily recognized for its potential use in the treatment of neurological disorders, particularly in the context of neuroprotection and as a calcium channel blocker. It is classified as a phenylpiperazine derivative and exhibits properties that may influence neurotransmitter release and neuronal excitability. Lifarizine has been studied for its ability to modulate calcium influx in cells, which is crucial for various physiological processes, including muscle contraction and neurotransmitter release. The compound has shown promise in preclinical studies for its neuroprotective effects, potentially offering therapeutic benefits in conditions such as ischemia and neurodegenerative diseases. Its pharmacological profile suggests that it may also possess antihypertensive and antianginal properties. However, further research is necessary to fully elucidate its mechanisms of action, efficacy, and safety in clinical settings. As with many compounds in this category, understanding its interactions with other medications and its overall pharmacokinetics is essential for its potential therapeutic applications.
Formula:C29H32N4
InChI:InChI=1/C29H32N4/c1-22-13-15-26(16-14-22)29-30-23(2)27(31-29)21-32-17-19-33(20-18-32)28(24-9-5-3-6-10-24)25-11-7-4-8-12-25/h3-16,28H,17-21H2,1-2H3,(H,30,31)
Synonyms:- 1-(diphenylmethyl)-4-{[5-methyl-2-(4-methylphenyl)-1H-imidazol-4-yl]methyl}piperazine
- Lifarizine [USAN:INN:BAN]
- UNII-C3705I245K
- Lyfarizine
- 1-(Diphenylmethyl)-4-((5-methyl-2-p-tolylimidazol-4-yl)methyl)piperazine
- RS 87476-000
- Piperazine, 1-(diphenylmethyl)-4-((5-methyl-2-(4-methylphenyl)-1H-imidazol-4-yl)methyl)-
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Found 2 products.
Lifarizine
CAS:Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion.Formula:C29H32N4Purity:99.88%Color and Shape:SolidMolecular weight:436.59
