CAS 119567-79-2

Viramidine

Description:

Viramidine is an antiviral compound primarily studied for its potential use in treating viral infections, particularly those caused by hepatitis C virus (HCV). It belongs to the class of nucleoside analogs, which mimic the structure of natural nucleosides, thereby interfering with viral replication. The chemical structure of Viramidine features a modified ribonucleoside backbone, which enhances its stability and bioavailability compared to its predecessors. This compound exhibits a mechanism of action that involves the inhibition of viral RNA polymerase, ultimately leading to reduced viral load. Viramidine has been evaluated in various preclinical and clinical studies, demonstrating promising antiviral activity. Its pharmacokinetic profile suggests favorable absorption and distribution characteristics, although specific details may vary based on formulation and administration routes. As with many antiviral agents, the efficacy and safety profile of Viramidine are critical for its therapeutic application, and ongoing research continues to explore its potential in combination therapies for enhanced antiviral effects.

Formula: C₈H₁₃N₅O₄

InChI: InChI=1S/C8H13N5O4/c9-6(10)7-11-2-13(12-7)8-5(16)4(15)3(1-14)17-8/h2-5,8,14-16H,1H2,(H3,9,10)/t3-,4-,5-,8-/m1/s1

InChI key: InChIKey=NHKZSTHOYNWEEZ-AFCXAGJDSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2N=C(C(=N)N)N=C2

Synonyms:

• 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboximidamide
• 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboximidine
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide
• 1H-1,2,4-Triazole-3-carboximidamide, 1-beta-D-ribofuranosyl-
• 1H-1,2,4-Triazole-3-carboximidamide, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• Icn 3142
• Ribamidine
• Ribavirin amidine
• Unii-R3B1994K2E
• Viramidine
• Taribavirin
• 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide

1H-1,2,4-Triazole-3-carboximidamide, 1-β-D-ribofuranosyl-

CAS: 119567-79-2

Formula: C₈H₁₃N₅O₄

Molecular weight: 243.2199

Ref: IN-DA0010OO

Viramidine

CAS: 119567-79-2

Viramidine is a nucleotide analogue prodrug, which is derived from naturally occurring nucleosides, specifically optimized for enhanced therapeutic profiles. Its mode of action involves conversion into ribavirin triphosphate within the body. This active form inhibits viral RNA polymerase, a critical enzyme necessary for viral replication. By disrupting the synthesis of viral RNA, Viramidine effectively reduces viral proliferation within host cells.

Purity: Min. 95%

Ref: 3D-AV178051

Taribavirin

CAS: 119567-79-2

Taribavirin: oral drug targeting HCV in liver, spares RBCs to reduce risk of anemia.

Formula: C₈H₁₃N₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 243.22

Ref: TM-T16993