CAS 1196109-52-0

N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide

Description:

N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide, identified by its CAS number 1196109-52-0, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple aromatic rings and functional groups. This compound features a piperidine ring, which contributes to its potential biological activity, and a trifluoromethyl group that enhances lipophilicity and may influence its pharmacokinetic properties. The presence of pyridine rings suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Its structure indicates that it may act as a ligand or inhibitor in various biochemical pathways. The compound's solubility, stability, and reactivity are influenced by its functional groups, which can affect its application in research or therapeutic contexts. Overall, this compound exemplifies the intricate design often found in drug development, where specific modifications are made to optimize efficacy and selectivity for desired biological targets.

Formula: C₂₄H₂₃F₃N₄O₂

InChI: InChI=1S/C24H23F3N4O2/c25-24(26,27)19-6-7-22(29-15-19)33-21-5-1-3-18(14-21)13-17-8-11-31(12-9-17)23(32)30-20-4-2-10-28-16-20/h1-7,10,14-17H,8-9,11-13H2,(H,30,32)

InChI key: InChIKey=NBOJHRYUGLRASX-UHFFFAOYSA-N

SMILES: C(NC=1C=CC=NC1)(=O)N2CCC(CC3=CC(OC4=CC=C(C(F)(F)F)C=N4)=CC=C3)CC2

Synonyms:

• 1-Piperidinecarboxamide, N-3-pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-
• Pf-3845
• N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide
• N-pyridin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methyl]piperidine-1-carboxamide
• N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxami
• PF3845/PF-3845
• CS-124
• PF-3845;PF 3845;PF3845
• 4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)benzyl)-N-(pyridin-3-yl)piperidine-1-carboxamide
• N-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide
• PF 3845 USP/EP/BP
• N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide hydrate
• PF 3845 hydrate

PF 3845 hydrate

CAS: 1196109-52-0

Formula: C₂₄H₂₃F₃N₄O₂·xH₂O

Molecular weight: 456.46 (anhydrous)

Ref: 7W-GK5770

PF-3845

CAS: 1196109-52-0

PF-3845

Purity: ≥98%

Molecular weight: 456.46g/mol

Ref: 54-BUP05836

PF-3845

CAS: 1196109-52-0

PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.

Formula: C₂₄H₂₃F₃N₄O₂

Purity: 99.54% - 99.58%

Color and Shape: Solid

Molecular weight: 456.46

Ref: TM-T6043

PF 3845

Controlled Product

CAS: 1196109-52-0

Applications PF 3845 is a selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 μM). Reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. Highly efficacious and selective in vivo. Displays no activity at FAAH-2 (IC50 >10 μM).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ahn, et al.: Chem. Biol., 16, 411 (2009), Ahn, et al.: Expert. Opin. Drug Discov., 4 763 (2009),

Formula: C₂₄H₂₃F₃N₄O₂

Color and Shape: Neat

Molecular weight: 456.46

Ref: TR-P293760

PF 3845

CAS: 1196109-52-0

Inhibitor of fatty acid amide hydrolase

Formula: C₂₄H₂₃F₃N₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 456.46 g/mol

Ref: 3D-FP102746