CAS 1196147-73-5

7-(Trifluoromethyl)-1-isoquinolinamine

Description:

7-(Trifluoromethyl)-1-isoquinolinamine is a chemical compound characterized by its isoquinoline structure, which features a nitrogen atom within a bicyclic aromatic system. The presence of a trifluoromethyl group (-CF3) at the 7-position significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the isoquinoline moiety's known bioactivity. The trifluoromethyl group can also enhance metabolic stability and alter the compound's interaction with biological targets. As with many nitrogen-containing heterocycles, it may participate in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions. Safety and handling precautions should be observed, as with all chemical substances, particularly those with halogenated groups, which may pose environmental and health risks.

Formula: C₁₀H₇F₃N₂

InChI: InChI=1S/C10H7F3N2/c11-10(12,13)7-2-1-6-3-4-15-9(14)8(6)5-7/h1-5H,(H2,14,15)

InChI key: InChIKey=CRYOQIQUMYQAKN-UHFFFAOYSA-N

SMILES: NC=1C2=C(C=CC(C(F)(F)F)=C2)C=CN1

Synonyms:

• 7-(Trifluoromethyl)isoquinoline-1-amine
• 7-(Trifluoromethyl)-1-isoquinolinamine
• 1-Isoquinolinamine, 7-(trifluoromethyl)-